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TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327847(CHEMBL1257517 | US8501783, 1591 | 1-(1-(Trifluoroa...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327850(US8501783, 1711 | CHEMBL1257759 | 1-(1-Tosylpiperi...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM2197(US8501783, 1591)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591334(CHEMBL5191146 | US20240182406, Example 3)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591340(CHEMBL5203787 | US20240182406, Example 4)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679460(1-(9-chloro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591341(CHEMBL5177372 | US20240182406, Example 7)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591336(CHEMBL5179027 | US20240182406, Example 8)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591337(CHEMBL5192445 | US20240182406, Example 10)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679468(4-(4-(3-(9-chloro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679469(4-(4-(3-(9-chloro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591331(CHEMBL5197282 | US20240182406, Example C3)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591330(CHEMBL5197431 | US20240182406, Example C11)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679467(4-(4-(3-(9-fluoro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.5nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679459(1-(9-fluoro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-...)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591338(CHEMBL5203245 | US20240182406, Example 9)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591335(CHEMBL5179500 | US20240182406, Example 11)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591333(CHEMBL5197313 | US20240182406, Example 12)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327856(CHEMBL1257880 | US8501783, 1710 | 1-(1-(5-(Dimethy...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100436(US8501783, 1702)
Affinity DataIC50: 0.900nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679477(1-(1-acetylpiperidin-4-yl)-3-(2-fluoro-9-methyl-5,...)
Affinity DataIC50: 0.900nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679478(1-(1-acetylpiperidin-4-yl)-3-(1-fluoro-9-methyl-5,...)
Affinity DataIC50: 0.900nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50551715(CHEMBL4741234)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of tissue extract derived mEH (unknown origin) using [3H]trans-stilbene oxide as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591329(CHEMBL5179393 | US20240182406, Example C7)
Affinity DataIC50: 1nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM2210(US8501783, 1209 | US8501783, 1203)
Affinity DataIC50: 1.10nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM2211(US8501783, 1211 | US8501783, 1204)
Affinity DataIC50: 1.10nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100412(US8501783, 1590)
Affinity DataIC50: 1.10nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100431(US8501783, 1204)
Affinity DataIC50: 1.10nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50581720(CHEMBL5080024 | US20240182406, Example C4)
Affinity DataIC50: 1.10nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50591328(CHEMBL5193653 | US20240182406, Example C6)
Affinity DataIC50: 1.10nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100430(US8501783, 1201)
Affinity DataIC50: 1.20nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679479(1-(1-acetylpiperidin-4-yl)-3-(2-methoxy-9-methyl-5...)
Affinity DataIC50: 1.20nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100428(US8501783, 1159)
Affinity DataIC50: 1.30nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100435(US8501783, 1701)
Affinity DataIC50: 1.40nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM2211(US8501783, 1211 | US8501783, 1204)
Affinity DataIC50: 1.5nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679474(1-(1-benzylpiperidin-4-yl)-3-(9-methyl-5,6,8,9,10,...)
Affinity DataIC50: 1.5nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100368(US8501783, 1433)
Affinity DataIC50: 1.70nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100378(US8501783, 1202)
Affinity DataIC50: 1.70nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100425(US8501783, 1606)
Affinity DataIC50: 1.70nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100383(US8501783, 1210)
Affinity DataIC50: 1.80nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100401(US8501783, 1556)
Affinity DataIC50: 1.80nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100367(US8501783, 1434)
Affinity DataIC50: 2.10nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50551715(CHEMBL4741234)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human mEH using CMNGC as substrate preincubated for 5 mins followed by substrate addition and measured at 30 secs interval for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100427(US8501783, 1157)
Affinity DataIC50: 2.64nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100377(US8501783, 1206)
Affinity DataIC50: 2.70nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM679481(1-(1-(4-acetylphenyl)piperidin-4-yl)-3-(9-methyl-5...)
Affinity DataIC50: 2.90nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100426(US8501783, 1163)
Affinity DataIC50: 3.19nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100363(US8501783, 1163 | US9296693, 2)
Affinity DataIC50: 3.20nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

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