Compile Data Set for Download or QSAR
Report error Found 347 for UniProtKB: P06935
LigandPNGBDBM33247(benzenecarboximidamide, 1)
Affinity DataKd:  1.50E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM33249(4-nitrophenyl 4-carbamimidamidobenzoate, 2)
Affinity DataKd:  1.60E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50468907(CHEMBL549740)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to West Nile virus NS3 protease by 15N-HSQC 1H NMR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50542238(CHEMBL4640778)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50468907(CHEMBL549740)
Affinity DataKd:  4.00E+4nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease assessed as dissociation constant by NMR spectroscopic anlaysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50513893(CHEMBL506092)
Affinity DataIC50: 56nMAssay Description:Inhibition of West Nile virus proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of West Nile virus NS2B (1393 to 1440 residues)-NS3 (1476 to 1687 residues) protease expressed in Escherichia coli BL21 (DE3) codon plus c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM35509(SMR000021572 | 2-thiophenecarboxylic acid [5-amino...)
Affinity DataIC50: 110nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM35509(SMR000021572 | 2-thiophenecarboxylic acid [5-amino...)
Affinity DataIC50: 110nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50: 120nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50212335(CHEMBL5275144)
Affinity DataIC50: 120nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 (DE3) RILP codon plus competent cells using Benzoyl-NleKRR-AMC as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50: 120nMAssay Description:Inhibition of West Nile virus NS2B (49 to 96 residues)-NS3 (2 to 184 residues) protease expressed in Escherichia coli BL21-rosetta cells using Bz-Nle...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM39394(SMR000021571 | cid_3240579 | 5-amino-1-[(4-methoxy...)
Affinity DataIC50: 297nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50302021(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50: 310nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50030457(CHEMBL3344314)
Affinity DataIC50: 380nMAssay Description:Inhibition of West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50030458(CHEMBL3344313)
Affinity DataIC50: 420nMAssay Description:Inhibition of West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50218663(CHEMBL5269219)
Affinity DataIC50: 440nMAssay Description:Inhibition of 6his tagged West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 CodonPlus (DE3)-RIPL cells using Pyr-RTKR-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50587014(CHEMBL5094815)
Affinity DataIC50: 460nMAssay Description:Inhibition of C-terminal His-tagged WNV NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease expressed in Escherichia coli BL21(DE3) using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567470(CHEMBL4862353)
Affinity DataIC50: 510nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM32761(MLS000033887 | Furan-2-carboxylic acid 5-amino-1-(...)
Affinity DataIC50: 553nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Lys-Arg-Arg-AMC as substrate assessed as proteolytic activ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109138(CHEMBL3601351)
Affinity DataIC50: 750nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567467(CHEMBL4850391)
Affinity DataIC50: 780nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50: 800nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)-Tyr substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567473(CHEMBL4872757)
Affinity DataIC50: 820nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567469(CHEMBL4856850)
Affinity DataIC50: 870nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567468(CHEMBL4853830)
Affinity DataIC50: 930nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50302022(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50: 970nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109050(CHEMBL3601349)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109046(CHEMBL3601345)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109139(CHEMBL3601352)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM32783(5-amino-1-[(4-fluorophenyl)sulfonyl]-1H-pyrazol-3-...)
Affinity DataIC50: 1.16E+3nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50542823(CHEMBL4633312)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli using Phe-Ala-Ser-Gly-Lys-Arg-pNA assessed as proteolytic cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50302023(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM39396(SMR000021561 | cid_3242592 | MLS000044151 | 5-amin...)
Affinity DataIC50: 1.26E+3nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109142(CHEMBL3601354)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567471(CHEMBL4876865)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50567472(CHEMBL4848934)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109047(CHEMBL3601346)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM32778([2-(2-cyanoethyl)-5-methyl-pyrazol-3-yl] benzoate ...)
Affinity DataIC50: 1.35E+3nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM32778([2-(2-cyanoethyl)-5-methyl-pyrazol-3-yl] benzoate ...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109049(CHEMBL3601348)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50127623(CHEMBL3628260)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)-Tyr substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM32756(CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...)
Affinity DataIC50: 1.65E+3nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109048(CHEMBL3601347)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109112(CHEMBL3601350)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50109265(CHEMBL3601102)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 347 total ) | Next | Last >>
Jump to: