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TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50407496(CHEMBL5284382)
Affinity DataIC50: 5nMAssay Description:Inhibition of human DNA polymerase beta by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50638112(CHEMBL5557939)
Affinity DataIC50: 204nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50293303(gallic acid 5,6-dihydroxy-3-carboxyphenylester | C...)
Affinity DataKi:  390nMAssay Description:Inhibition of DNA polymerase beta from human KB3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623038(CHEMBL5431041)
Affinity DataIC50: 400nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253141([(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,...)
Affinity DataKi:  600nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253100([(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-...)
Affinity DataKi:  900nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253142([(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50241922(CHEMBL486991 | sodium ((2S,5R)-5-(4-amino-2-oxopyr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50335554(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50638112(CHEMBL5557939)
Affinity DataKi:  1.80E+3nMAssay Description:Irreversible inhibition of DNA polymerase beta (unknown origin) assessed as inhibition constant by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184757((3aR,4R,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50292441(1beta-hydroxyaleuritolic acid 3-p-hydroxybenzoate ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408426(CHEMBL2092833)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184758((3aS,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184756((3aR,4S,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184752((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(isopropoxy...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623035(CHEMBL1977402)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA polymerase beta incubated for 30 mins in presence of dNTP by PAGE based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623036(CHEMBL1985644)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA polymerase beta incubated for 30 mins in presence of dNTP by PAGE based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50377969(CHEMBL1162297)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50615505(CHEMBL5290566)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50250356(protolichesterinic acid | (+)-protolichesterinic a...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | CHEM...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | CHEM...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184748((2S,3S,4R)-methyl 2-ethyl-4-hydroxy-5-(2-oxononade...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184761((3aR,4R,7S,7aS)-dimethyl 3,5-dihexadecyl-1-oxo-7-(...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184754((E)-methyl-3,6-dioxo-4-docosenoate | CHEMBL425779)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50079577((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184750((2R,3S,4R)-4-hydroxy-5-[2-oxo-nonadec-ylidene]-1-p...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181932(2-(4-(bis(4-chlorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181938(1-Cyclohexyl-2-[2-fluoro-4-(phenyl-pyridin-3-yl-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181927(2-(4-(bis(4-fluorophenyl)methoxy)-2-fluorophenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184759((2R,3S,4R)-methyl 1-(2-(1H-indol-3-yl)ethyl)-4-hyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181935(1-Cyclohexyl-2-[4-(di-pyridin-3-yl-methoxy)-2-fluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181923(2-(4-(benzhydryloxy)phenyl)-1-cyclohexyl-1H-benzo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181941(2-(4-(benzhydryloxy)-2-fluorophenyl)-1-cyclohexyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181926(2-{4-[Bis-(4-dimethylcarbamoyl-phenyl)-methoxy]-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50191511(2-{4-[4'-chloro-4-(2-oxopyrrolidin-1-yl)biphenyl-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50181922(2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50241929(Mahureone D | CHEMBL520861)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50242105(armenin-B | CHEMBL470873)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of DNA polymerase beta lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184753((1R,1bR,2R,5S,5aS)-1a,3-dihexadecyl-6-oxo-1a,1b,2,...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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