Compile Data Set for Download or QSAR
Report error Found 93 for UniProtKB: P01112
LigandPNGBDBM707344(US20240408064, Compound 10018)
Affinity DataKd:  3.36E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707352(1-(azetidin-1-yl)-2-(6-fluoro-1H-indol-3-yl) propa...)
Affinity DataKd:  3.75E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707351(US20240408064, Compound 10053)
Affinity DataKd:  1.53E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707350(US20240408064, Compound 10041)
Affinity DataKd:  7.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707349(US20240408064, Compound 10040)
Affinity DataKd:  6.77E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707348(1-(azetidin-1-yl)-2-(5-fluoro-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKd:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707347(US20240408064, Compound 10027)
Affinity DataKd:  7.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707346(US20240408064, Compound 10026)
Affinity DataKd:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707345(US20240408064, Compound 10025)
Affinity DataKd:  6.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707361(US20240408064, Compound FS-1255)
Affinity DataKd:  6.07E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707343(US20240408064, Compound 10014)
Affinity DataKd:  2.32E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707342(US20240408064, Compound 10006)
Affinity DataKd:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707341(US20240408064, Compound 10004)
Affinity DataKd:  6.28E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707340(US20240408064, Compound 10002)
Affinity DataKd:  2.51E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50520329(CHEMBL4550896)
Affinity DataKd: >3.70E+5nMAssay Description:Inhibition GST-tagged recombinant HRAS G12V mutant (1 to 166 amino acids) (unknown origin) expressed in Escherichia coli C41(DE3) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50520327(CHEMBL4456044)
Affinity DataKd:  51nMAssay Description:Inhibition GST-tagged recombinant HRAS G12V mutant (1 to 166 amino acids) (unknown origin) expressed in Escherichia coli C41(DE3) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  1.58E+5nMAssay Description:Binding affinity to His6-tagged HRas-GDP expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to His6-tagged HRas expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM707353(US20240408064, Compound 10086)
Affinity DataKd:  1.95E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707344(US20240408064, Compound 10018)
Affinity DataKd:  5.18E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707360(US20240408064, Compound 11032)
Affinity DataKd:  452nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707360(US20240408064, Compound 11032)
Affinity DataKd:  772nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707360(US20240408064, Compound 11032)
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707359(US20240408064, Compound 10160)
Affinity DataKd:  1.28E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707358(US20240408064, Compound 10159)
Affinity DataKd:  3.19E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707357(US20240408064, Compound 10114)
Affinity DataKd:  1.11E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707356(US20240408064, Compound 10106)
Affinity DataKd:  6.43E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707355(US20240408064, Compound 10097)
Affinity DataKd:  8.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707355(US20240408064, Compound 10097)
Affinity DataKd:  3.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707355(US20240408064, Compound 10097)
Affinity DataKd:  7.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707355(US20240408064, Compound 10097)
Affinity DataKd:  108nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707354(N-(3-(2-(dimethylamino)ethoxy)phenyl)-2-(6-fluoro-...)
Affinity DataKd:  2.13E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707354(N-(3-(2-(dimethylamino)ethoxy)phenyl)-2-(6-fluoro-...)
Affinity DataKd:  36nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707353(US20240408064, Compound 10086)
Affinity DataKd:  3.18E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50092365((R)-3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-(thiophe...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HRAS (unknown origin) farnesylationMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50092365((R)-3-Benzyl-1-(3H-imidazol-4-ylmethyl)-4-(thiophe...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human H-rasMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50063453(1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of H-Ras (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089967(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089960(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089961(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1-...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089962(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-be...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089969(5-[Bis-(2-chloro-ethyl)-amino]-benzofuran-2-carbox...)
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089971(5-[Bis-(2-chloro-ethyl)-amino]-1-methyl-1H-indole-...)
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50089978(5-[Bis-(2-chloro-ethyl)-amino]-1H-indole-2-carboxy...)
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50060139([(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cyclobuty...)
Affinity DataIC50: 88nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50601400(CHEMBL5171806)
Affinity DataIC50: 100nMAssay Description:Inhibition of HRAS (unknown origin) transfected in BALB/c nude mouse incubated for 3 days measured by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50601398(CHEMBL5174384)
Affinity DataIC50: 100nMAssay Description:Inhibition of [35S]methionine labelled HRAS in rat Rat1 cells by immunoprecipitation analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50060141([(S)-1-{(4-Benzyloxy-benzyl)-[(2-methyl-2-phenyl-p...)
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50060146([(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cycloprop...)
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGTPase HRas(Human)
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50060140([(S)-1-{(4-Benzyloxy-benzyl)-[(2-cyano-2-phenyl-et...)
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 93 total ) | Next | Last >>
Jump to: