Compile Data Set for Download or QSAR
Report error Found 19 of affinity data for UniProtKB/TrEMBL: O60906
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50407385(CHEMBL5284450)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant nSMaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50407383(CHEMBL5278618)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant nSMaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against schyphostatin of neutral sphingomyelinase (N-SMase) from bovine brain microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50407376(CHEMBL5284579)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of nSMase in human U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50407377(CHEMBL5270975)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of nSMase in human U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50221658(CHEMBL110491)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50221662(CHEMBL320658)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50221661(CHEMBL110445)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50214969(Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50221660(CHEMBL109045)
Affinity DataIC50: 2.02E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50221659(CHEMBL107844)
Affinity DataIC50: 2.92E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122310(((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...)
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122310(((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...)
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122311({2-[((E)-(3S,4R)-1,1-Difluoro-4-hydroxy-3-octadeca...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50122310(((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...)
Affinity DataKi:  2.53E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed