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Report error Found 12 of affinity data for UniProtKB/TrEMBL: O35240
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548045(CHEMBL4757433)
Affinity DataEC50:  3.00E+3nMAssay Description:Modulation of rat ASIC3 expressed in Xenopus laevis oocytes at -70 mV holding potential by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)
Affinity DataIC50: 950nMAssay Description:Inhibition of rat ASIC3 assessed as inhibition of peak current by patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50157090(6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ASIC3 in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 2.29E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50250133(Butibufen)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50250130(CHEMBL4083814)
Affinity DataIC50: 3.02E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50: 3.09E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50295285(Ibufenac | (4-Isobutyl-phenyl)-acetic acid | 2-(4-...)
Affinity DataIC50: 4.17E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 5.13E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50250131(CHEMBL190275)
Affinity DataIC50: 7.08E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50250132(CHEMBL4080879)
Affinity DataIC50: 8.91E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed