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Report error Found 27 of affinity data for UniProtKB/TrEMBL: O26232
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | {[(2R,3S,4R,5R...)
Affinity DataKi:  190nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | {[(2R,3S,4R,5R...)
Affinity DataKi:  200nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27944({[(2R,3S,4R,5R)-5-(6-azido-5-fluoro-2,4-dioxo-1,2,...)
Affinity DataKi:  360nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341908(((2S,3S,4R,5R)-5-(5-azido-2,4-dioxo-3,4-dihydropyr...)
Affinity DataKi:  630nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(JMC521648 Compound 37 | 6-Amino-uridine 5-O-Monoph...)
Affinity DataKi:  840nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(JMC521648 Compound 37 | 6-Amino-uridine 5-O-Monoph...)
Affinity DataKi:  840nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(JMC521648 Compound 37 | 6-Amino-uridine 5-O-Monoph...)
Affinity DataKi:  840nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50459997(CHEBI:90284 | 47599 | Pirazofurin | Pyrazofurin)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM47402(2-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidany...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  1.11E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27945({[(2R,3S,4R,5R)-5-(6-amino-5-fluoro-2,4-dioxo-1,2,...)
Affinity DataKi:  1.14E+4nM ΔG°:  -31.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340({[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340({[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,...)
Affinity DataKi:  1.24E+4nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(JMC521648 Compound 34 | 6-cyanouridine 5-monophosp...)
Affinity DataKi:  2.90E+4nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27946({[(2R,3S,4R,5R)-5-(6-ethyl-5-fluoro-2,4-dioxo-1,2,...)
Affinity DataKi:  2.90E+4nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(JMC521648 Compound 34 | 6-cyanouridine 5-monophosp...)
Affinity DataKi:  2.90E+4nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(JMC521648 Compound 34 | 6-cyanouridine 5-monophosp...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341905(ammonium 6-Cyano-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | JMC521648 Com...)
Affinity DataKi:  1.34E+5nM ΔG°:  -24.3kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | JMC521648 Com...)
Affinity DataKi:  1.34E+5nM ΔG°:  -24.3kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341907(ammonium 5-Cyano-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27943({[(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-1,2,3,4-tetr...)
Affinity DataKi:  6.45E+5nM ΔG°:  -20.0kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341906(Ammonium 6-Amido-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  3.32E+6nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341909(ammonium 6-Azido-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  1.20E+6nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341905(ammonium 6-Cyano-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  3.00E+7nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed