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Report error Found 1182 of affinity data for UniProtKB/TrEMBL: O00141
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  28nMAssay Description:Binding affinity to SGK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  566nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  331nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697107(US20240309005, Compound 22)
Affinity DataIC50: 0.272nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM269143(US9718825, Example 589)
Affinity DataIC50: 0.5nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM269150(US9718825, Example 596)
Affinity DataIC50: 0.5nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697119(US20240309005, Compound 38)
Affinity DataIC50: 0.508nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697142(US20240309005, Compound 84)
Affinity DataIC50: 0.508nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268829(US9718825, Example 234)
Affinity DataIC50: 0.510nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM269083(US9718825, Example 527)
Affinity DataIC50: 0.510nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM269008(US9718825, Example 451)
Affinity DataIC50: 0.570nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268860(US9718825, Example 265)
Affinity DataIC50: 0.590nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697114(US20240309005, Compound 29)
Affinity DataIC50: 0.595nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697143(US20240309005, Compound 85)
Affinity DataIC50: 0.600nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697136(US20240309005, Compound 73)
Affinity DataIC50: 0.631nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697094(US20240309005, Compound 9)
Affinity DataIC50: 0.730nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268850(US9718825, Example 261 | US9718825, Example 255)
Affinity DataIC50: 0.760nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268828(US9718825, Example 233)
Affinity DataIC50: 0.850nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM697146(US20240309005, Compound 154)
Affinity DataIC50: 0.980nMAssay Description:The compounds were tested for SGK-1 activity by measuring the ability of the compound to inhibit the transfer of phosphate from ATP by the isolated e...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 1nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumine...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043877(CHEMBL3356033)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043878(CHEMBL3356034)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043894(CHEMBL3356037)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043926(CHEMBL3356021)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043928(CHEMBL3356023)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043930(CHEMBL3356025)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043934(CHEMBL3356029)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043935(CHEMBL3356030)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50043937(CHEMBL3356032)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584096(CHEMBL5078023)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584097(CHEMBL5084696)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584100(CHEMBL5093306)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584101(CHEMBL5087657)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584102(CHEMBL5075992)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584106(CHEMBL5080922)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584107(CHEMBL5077567)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584109(CHEMBL5071237)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584111(CHEMBL5090286)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584112(CHEMBL5079183)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584115(CHEMBL5081215)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584117(CHEMBL5075362)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584122(CHEMBL5074684)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268933(US9718825, Example 359)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584127(CHEMBL5087162)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268914(US9718825, Example 339)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50584128(CHEMBL5083625)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM268850(US9718825, Example 261 | US9718825, Example 255)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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