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Report error Found 260 of affinity data for UniProtKB/TrEMBL: A5H660
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataKd:  367nMAssay Description:Binding affinity to Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataKd:  82nMAssay Description:Binding affinity to Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataKd:  28nMAssay Description:Binding affinity to Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50: 68nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164518(CHEMBL3800394)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164518(CHEMBL3800394)
Affinity DataIC50: 76nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164531(CHEMBL3799246)
Affinity DataIC50: 91nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164531(CHEMBL3799246)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50: 95nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)
Affinity DataIC50: 95nMAssay Description:Inhibition of Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluoro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50450625(CHEMBL4160522)
Affinity DataIC50: 97nMAssay Description:Inhibition of Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluoro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578956(CHEMBL4853162)
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578957(CHEMBL4855490)
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578966(CHEMBL4867041)
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164519(CHEMBL3799297)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164519(CHEMBL3799297)
Affinity DataIC50: 107nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578958(CHEMBL4849600)
Affinity DataIC50: 110nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578967(CHEMBL4852163)
Affinity DataIC50: 110nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164538(CHEMBL3797597)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164538(CHEMBL3797597)
Affinity DataIC50: 117nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164522(CHEMBL3797442)
Affinity DataIC50: 120nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164522(CHEMBL3797442)
Affinity DataIC50: 122nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164515(CHEMBL3798028)
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164515(CHEMBL3798028)
Affinity DataIC50: 129nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164514(CHEMBL3799728)
Affinity DataIC50: 138nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164514(CHEMBL3799728)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578978(CHEMBL4870162)
Affinity DataIC50: 140nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164520(CHEMBL3798503)
Affinity DataIC50: 145nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164520(CHEMBL3798503)
Affinity DataIC50: 146nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50: 148nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578975(CHEMBL4870316)
Affinity DataIC50: 150nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50: 151nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578974(CHEMBL4870946)
Affinity DataIC50: 160nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578981(CHEMBL4850958)
Affinity DataIC50: 170nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164597(CHEMBL3798925)
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164597(CHEMBL3798925)
Affinity DataIC50: 178nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50567345(CHEMBL4872913)
Affinity DataIC50: 180nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578979(CHEMBL4846424)
Affinity DataIC50: 180nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578983(CHEMBL4874213)
Affinity DataIC50: 180nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164524(CHEMBL3799265)
Affinity DataIC50: 182nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164524(CHEMBL3799265)
Affinity DataIC50: 183nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164539(CHEMBL3798870)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164530(CHEMBL3797232)
Affinity DataIC50: 191nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164530(CHEMBL3797232)
Affinity DataIC50: 191nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50164539(CHEMBL3798870)
Affinity DataIC50: 191nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50578971(CHEMBL4853828)
Affinity DataIC50: 200nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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