Reaction Details Report a problem with these data
Target
Cysteine protease falcipain-3 [5-492]
Ligand
BDBM50157746
Substrate
n/a
Meas. Tech.
ChEMBL_430127 (CHEMBL919605)
IC50
>50000±n/a nM
Citation
 Desai, PV; Patny, A; Sabnis, Y; Tekwani, B; Gut, J; Rosenthal, P; Srivastava, A; Avery, M Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. J Med Chem 47:6609-15 (2004) [PubMed]  Article 
Target
Name:
Cysteine protease falcipain-3 [5-492]
Synonyms:
Q9NAW4_PLAFA | Cysteine protease falcipain-3
Type:
PROTEIN
Mol. Mass.:
56106.86
Organism:
malaria parasite P. falciparum
Description:
ChEMBL_430127
Residue:
488
Sequence:
MEYSPNEVIKQEREVFVGKEKSGSKFKRKRSIFIVLTVSICFMFALMLFYFTRNENNKTLFTNSLSNNINDDYIINSLLKSESGKKFIVSKLEELISSYDKEKKMRTTGAEENNMNMNGIDDKDNKSVSFVNKKNGNLKVNNNNQVSYSNLFDTKFLMDNLETVNLFYIFLKENNKKYETSEEMQKRFIIFSENYRKIELHNKKTNSLYKRGMNKFGDLSPEEFRSKYLNLKTHGPFKTLSPPVSYEANYEDVIKKYKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVKNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIPDDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLLE
  
Inhibitor
Name:
BDBM50157746
Synonyms:
N'-(4-(2-(4-fluorophenylamino)-2-oxoethoxy)benzylidene)-2-cyanoacetohydrazide | CHEMBL374510
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: