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Target
Metabotropic glutamate receptor 4
Ligand
BDBM50004051
Substrate
n/a
Meas. Tech.
ChEMBL_106701 (CHEMBL714003)
EC50
330±n/a nM
Citation
 Kozikowski, AP; Steensma, D; Araldi, GL; Tückmantel, W; Wang, S; Pshenichkin, S; Surina, E; Wroblewski, JT Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist. J Med Chem 41:1641-50 (1998) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
Metabotropic glutamate receptor 4 | metabotropic glutamate 4 | Glutamate receptor, metabotropic 4 | GRM4_HUMAN | GRM4 | GPRC1D | MGLUR4 | Metabotropic glutamate receptor 4 (mGluR4) | Metabotropic glutamate receptor 4 (mGlu4)
Type:
Protein
Mol. Mass.:
101899.95
Organism:
Human
Description:
Q14833
Residue:
912
Sequence:
MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM50004051
Synonyms:
CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | 4-Amino Phosphonobutyrate | GlcN-6-P synthase inhibitor, 1 (racemic mixture) | L-AP4 | 2-Amino-4-phosphono-butyric acid (AP4)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: