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Target
fMet-Leu-Phe receptor
Ligand
BDBM450281
Substrate
n/a
Meas. Tech.
Biological Assay
EC50
450±n/a nM
Citation
 Shirude, PS; Baligar, V; Seshadri, B; Chattopadhyay, AK; Wurtz, NR; Kick, EK Phenylpyrrolidinone formyl peptide 2 receptor agonists US Patent  US11117861 Publication Date 9/14/2021 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
Formyl peptide Receptor | formyl peptide receptor 1 | fMLP receptor | N-formylpeptide chemoattractant receptor | FPR | FPR1_HUMAN | FPR1 | fMet-Leu-Phe receptor | N-formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Human
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM450281
Synonyms:
US10676431, Example 44 | US11117861, Example 44
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC(NC(C)=O)c1cccc(c1)-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r|
Structure:
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