Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 2122
TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155261(US9006244, E4a | US9814715, Example 4, isomer 1)
Affinity DataKi:  4nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155257(US9006244, E2a | US9814715, Example 2, isomer 1)
Affinity DataKi:  20nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155259(US9006244, E3a | US9814715, Example 3, isomer 1)
Affinity DataKi:  27nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155261(US9006244, E4a | US9814715, Example 4, isomer 1)
Affinity DataKi:  43nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM354727(US9814715, Example 1 | 1-isopropyl-7-(methylsulfon...)
Affinity DataKi:  256nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155257(US9006244, E2a | US9814715, Example 2, isomer 1)
Affinity DataKi:  318nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155259(US9006244, E3a | US9814715, Example 3, isomer 1)
Affinity DataKi:  398nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155262(US9006244, E4b | US9814715, Example 4, isomer 2)
Affinity DataKi:  846nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155260(US9006244, E3b | US9814715, Example 3, isomer 2)
Affinity DataKi:  1.75E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM354727(US9814715, Example 1 | 1-isopropyl-7-(methylsulfon...)
Affinity DataKi:  1.77E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155258(US9006244, E2b | US9814715, Example 2, isomer 2)
Affinity DataKi: >2.50E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155258(US9006244, E2b | US9814715, Example 2, isomer 2)
Affinity DataKi: >3.33E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155260(US9006244, E3b | US9814715, Example 3, isomer 2)
Affinity DataKi: >3.33E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharamceuticals

US Patent
LigandPNGBDBM155262(US9006244, E4b | US9814715, Example 4, isomer 2)
Affinity DataKi: >3.33E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
Go to US Patent