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Found
13
Enz. Inhib. hit(s) with all data for entry = 12699
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720778
(US20250051367, Compound 1)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720779
(Synthesis of (R)-4-phenyl-1-((R)-2-(pyrazine-2-car...)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720780
(US20250051367, Compound 3)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720781
(Synthesis of ((R)-1-((R)-3-(1-methyl-1H-pyrazol-3-...)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720782
(US20250051367, Compound 5)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720783
(Synthesis of ((R)-1-((R)-3-(oxazol-5-yl)-2-(pyrazi...)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720787
(US20250051367, Compound 10)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720788
(Synthesis of ((R)-1-((R)-3-(oxazol-2-yl)-2-(pyrazi...)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720789
(US20250051367, Compound 12)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720784
(US20250051367, Compound 7)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720785
(US20250051367, Compound 8)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720786
(Synthesis of ((R)-3-methyl-1-((R)-3-(1-methyl-1H-I...)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM720790
(Synthesis of ((R)-1-((R)-3-(1-methyl-1H-Imidazol-2...)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL