Compile Data Set for Download or QSAR
Report error Found 119 Enz. Inhib. hit(s) with all data for entry = 11981
TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668001(US20240124434, Compound S5-A)
Affinity DataIC50: 860nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668000(US20240124434, Compound Ceapin-A7)
Affinity DataIC50: 960nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668015(US20240124434, Compound 99 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668003(US20240124434, Compound 11 | N-(1-(2,4- bis(triflu...)
Affinity DataIC50: 1.09E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668007(US20240124434, Compound 76 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 1.14E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 1.35E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 1.80E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668001(US20240124434, Compound S5-A)
Affinity DataIC50: 2.30E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668001(US20240124434, Compound S5-A)
Affinity DataIC50: 2.31E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Altos Labs

US Patent
LigandPNGBDBM668016(US20240124434, Compound 138 | N-(1-(1-(2,4- bis(tr...)
Affinity DataIC50: 2.40E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668001(US20240124434, Compound S5-A)
Affinity DataIC50: 2.49E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668015(US20240124434, Compound 99 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 2.50E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 2.78E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668009(US20240124434, Compound 121 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 2.90E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668001(US20240124434, Compound S5-A)
Affinity DataIC50: 3.07E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 3.54E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668007(US20240124434, Compound 76 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 3.60E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 4.18E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668015(US20240124434, Compound 99 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 4.80E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 4.97E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668016(US20240124434, Compound 138 | N-(1-(1-(2,4- bis(tr...)
Affinity DataIC50: 5.00E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 5.27E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 5.48E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668007(US20240124434, Compound 76 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 6.00E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 6.44E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668007(US20240124434, Compound 76 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 6.45E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668000(US20240124434, Compound Ceapin-A7)
Affinity DataIC50: 7.48E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668007(US20240124434, Compound 76 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 7.54E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668003(US20240124434, Compound 11 | N-(1-(2,4- bis(triflu...)
Affinity DataIC50: 7.77E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 7.88E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668015(US20240124434, Compound 99 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 8.80E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668003(US20240124434, Compound 11 | N-(1-(2,4- bis(triflu...)
Affinity DataIC50: 9.85E+3nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.07E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.08E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668016(US20240124434, Compound 138 | N-(1-(1-(2,4- bis(tr...)
Affinity DataIC50: 1.21E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.48E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668016(US20240124434, Compound 138 | N-(1-(1-(2,4- bis(tr...)
Affinity DataIC50: 1.50E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 1.53E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.54E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.58E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Altos Labs

US Patent
LigandPNGBDBM668006(US20240124434, Compound 131 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 1.64E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668003(US20240124434, Compound 11 | N-(1-(2,4- bis(triflu...)
Affinity DataIC50: 1.69E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Altos Labs

US Patent
LigandPNGBDBM668005(US20240124434, Compound 78 | N-(1-(1-(2,4- bis(tri...)
Affinity DataIC50: 2.24E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668004(US20240124434, Compound 154 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 2.26E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Altos Labs

US Patent
LigandPNGBDBM668009(US20240124434, Compound 121 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 2.36E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668002(US20240124434, Compound S6-A)
Affinity DataIC50: 2.37E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Altos Labs

US Patent
LigandPNGBDBM668009(US20240124434, Compound 121 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 3.05E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 1A2(Human)
Altos Labs

US Patent
LigandPNGBDBM668006(US20240124434, Compound 131 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 3.09E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 2C9(Human)
Altos Labs

US Patent
LigandPNGBDBM668010(US20240124434, Compound 123 | (R)-N-(1-(1-(2,4- bi...)
Affinity DataIC50: 3.19E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 2D6(Human)
Altos Labs

US Patent
LigandPNGBDBM668015(US20240124434, Compound 99 | (R)-N-(1-(1-(2,4- bis...)
Affinity DataIC50: 3.20E+4nMAssay Description:CYP inhibition by test compounds in human liver microsomes (HLM) for seven major CYP450 isoforms CYP1A2, CYP2C9, CYP2D6, CYP2B6, CYP2C8, CYP2C19 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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