Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 12243
TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM50090462(CHEMBL3581693 | US20240043442, Example GDC-0810 | ...)
Affinity DataKi:  0.370nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689297(US12054469, Compound 12 | (E)-3-(4-((2-(2,4- Dimet...)
Affinity DataKi:  0.5nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689510(US12054469, Compound 21 | (E)-3-(4-((2-(4-Chloro-2...)
Affinity DataKi:  0.570nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689295(US12054469, Compound 1)
Affinity DataKi:  0.650nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689511(US12054469, Compound 20)
Affinity DataKi:  0.730nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689287(US12054469, Compound 5 | (E)-3-(4-((6-Hydroxy-2-(2...)
Affinity DataKi:  1.29nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
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TargetEstrogen receptor(Human)
University of Illinois

US Patent
LigandPNGBDBM689509(US12054469, Compound 11 | (E)-3-(4-((2-(2,6- Dimet...)
Affinity DataKi:  2nMAssay Description:Binding affinities were also determined by a competitive radiometric binding assay using 2 nM [3H]estradiol as tracer (PerkinElmer, Waltham, MA) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent