Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 11179
TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191770(US9187406, Compound 7 | US10669227, Compound 7 | U...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191769(US9187406, Compound 6 | US11608309, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 4.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191767(US9187406, Compound 3 | US11608309, Compound 3)
Affinity DataIC50: 6.00E+3nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191767(US9187406, Compound 3 | US11608309, Compound 3)
Affinity DataIC50: 8.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 9.00E+3nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 1.40E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 1.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 1.60E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM597754(US11608309, Compound 4)
Affinity DataIC50: 1.70E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 2.25E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM445059(US10669227, Compound 5 | US11608309, Compound 5)
Affinity DataIC50: 2.80E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 2.90E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 3.50E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM597758(US11608309, Compound 8)
Affinity DataIC50: 4.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 4.80E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191767(US9187406, Compound 3 | US11608309, Compound 3)
Affinity DataIC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191769(US9187406, Compound 6 | US11608309, Compound 6)
Affinity DataIC50: 8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 1.10E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191770(US9187406, Compound 7 | US10669227, Compound 7 | U...)
Affinity DataIC50: 1.25E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM597754(US11608309, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM597754(US11608309, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent