Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 11116
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592182(US11572344, Example 10 | US11572344, Compound 1.01...)
Affinity DataIC50: 150nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592186(US11572344, Compound 1.017)
Affinity DataIC50: 150nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592189(US11572344, Compound 1.030)
Affinity DataIC50: 150nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592190(US11572344, Example 31 | US11572344, Compound 1.03...)
Affinity DataIC50: 150nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592177(US11572344, Compound 1.001)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592179(US11572344, Example 7 | US11572344, Compound 1.007)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592180(US11572344, Example 8 | US11572344, Compound 1.008)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592181(US11572344, Example 9 | US11572344, Compound 1.009)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592183(US11572344, Example 11 | US11572344, Compound 1.01...)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592184(US11572344, Example 12 | US11572344, Compound 1.01...)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592185(US11572344, Example 13 | US11572344, Compound 1.01...)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592187(US11572344, Compound 1.018)
Affinity DataIC50: 825nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592178(US11572344, Example 5 | US11572344, Compound 1.005)
Affinity DataIC50: 1.50E+3nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592188(US11572344, Compound 1.022)
Affinity DataIC50: 1.50E+3nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
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