Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 7971
TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226165(N'-[4-Methoxybenzylidene-2-(6-chloro)-3-(4-met...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 80nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226173(6-Chloro-2-((5-(4-chlorophenylamino)-1,3,4-thiadia...)
Affinity DataIC50: 400nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226170(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226163(2-[(6,7-Dimethoxy)-3-(4-methoxyphenyl)-4-oxo-3,4-d...)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226168(1-[2-(6-Chloro)-3-(4-methoxy-phenyl)-4-oxo-3,4-dih...)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226160(Ethyl 2-(6-chloro-3-(4-methoxyphenyl)-4-oxo-3,4-di...)
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226174(6-chloro-2-((5-(4-methoxyphenylamino)-1,3,4-thiadi...)
Affinity DataIC50: 4.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226162(2-[6-Chloro-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroq...)
Affinity DataIC50: 7.50E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226166(N'-[4-Chlorobenzylidene-2-(6,7-dimethoxy)-3-(4...)
Affinity DataIC50: 7.60E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226167(N'-[4-Methoxybenzylidene-2-(6,7-dimethoxy)-3-(...)
Affinity DataIC50: 8.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226172((6,7-Dimethoxy)-2-((4-(4-methoxyphenyl)-5-mercapto...)
Affinity DataIC50: 1.08E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226171((6,7-Dimethoxy)-2-((4-(4-chlorophenyl)-5-mercapto-...)
Affinity DataIC50: 1.10E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226158(6-Chloro-2-mercapto-3-(4-methoxyphenyl)quinazolin-...)
Affinity DataIC50: 1.15E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226176(6,7-Dimethoxy-2-((5-(4-methoxyphenylamino)-1,3,4-t...)
Affinity DataIC50: 1.18E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226161(Ethyl 2-(6,7-dimethoxy-3-(4-methoxyphenyl)-4-oxo-3...)
Affinity DataIC50: 1.44E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226175(6,7-Dimethoxy-2-((5-(4-chlorophenylamino)-1,3,4-th...)
Affinity DataIC50: 1.47E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226164(N'-[4-Chlorobenzylidene-2-(6-chloro)-3-(4-meth...)
Affinity DataIC50: 1.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226159((6,7-Dimethoxy)-2-mercapto-3-(4-methoxyphenyl)quin...)
Affinity DataIC50: 2.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226169(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50: 5.60E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details