Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50016563
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595738(CHEMBL1834164)
Affinity DataEC50:  1.83E+3nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50103601(CHEBI:29007 | Ceftriaxone)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595740(CHEMBL5202745)
Affinity DataEC50:  0.800nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595741(CHEMBL5208038)
Affinity DataEC50:  35nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595742(CHEMBL5181457)
Affinity DataEC50:  3.80nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595743(CHEMBL5207363)
Affinity DataEC50:  79nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 expressed in COS cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595740(CHEMBL5202745)
Affinity DataEC50:  0.800nMAssay Description:Activation of human EAAT2 expressed in COS cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  1nMAssay Description:Activation of human EAAT2 expressed in rat Astrocytes assessed as glutamate uptake by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50595740(CHEMBL5202745)
Affinity DataEC50:  0.300nMAssay Description:Activation of human EAAT2 expressed in rat Astrocytes assessed as glutamate uptake by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed