Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50015220
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584011(CHEMBL5077617)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584004(CHEMBL5076491)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584013(CHEMBL5082354)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 163nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50555067(CHEMBL4758344)
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584006(CHEMBL5083991)
Affinity DataIC50: 431nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584009(CHEMBL5077759)
Affinity DataIC50: 709nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584008(CHEMBL5087869)
Affinity DataIC50: 772nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584010(CHEMBL5090992)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584005(CHEMBL5080624)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584012(CHEMBL5079039)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584013(CHEMBL5082354)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584009(CHEMBL5077759)
Affinity DataIC50: 6.74E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584016(CHEMBL5078011)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584014(CHEMBL5091228)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584017(CHEMBL5091886)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584015(CHEMBL5084303)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584010(CHEMBL5090992)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584008(CHEMBL5087869)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584004(CHEMBL5076491)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584012(CHEMBL5079039)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP1A2 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2B6 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C8 preincubated for 10 min followed by addition of NADPH and measured after 45 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C9 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C19 preincubated for 10 min followed by addition of NADPH and measured after 45 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2D6 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A4 preincubated for 10 min followed by addition of NADPH and measured after 5 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A5(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A5 preincubated for 10 min followed by addition of NADPH and measured after 5 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584011(CHEMBL5077617)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Patch Clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50555067(CHEMBL4758344)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584005(CHEMBL5080624)
Affinity DataIC50: 4.22E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 4.64E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584006(CHEMBL5083991)
Affinity DataIC50: 8.45E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed