Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50016855
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50285416(CHEMBL4161733)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells in presence of heme measured after 20 hrs by heme-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50285417(CHEMBL4176866)
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562498(CHEMBL4797341)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549975(CHEMBL4747226)
Affinity DataIC50: 4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562497(CHEMBL4778760)
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597792(CHEMBL5196354)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597781(CHEMBL5201660)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597794(CHEMBL5173884)
Affinity DataIC50: 16nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50285524(CHEMBL4166767)
Affinity DataIC50: 18nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM370555(US10233190, Example 1488 | (1R,4r)-4-((R)-2-((S)-6...)
Affinity DataIC50: 28nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597786(CHEMBL5187577)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597787(CHEMBL5184643)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597789(CHEMBL5191625)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597790(CHEMBL5188903)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597785(CHEMBL5204616)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597784(CHEMBL5176069)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597783(CHEMBL5169351)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50550026(CHEMBL4786690)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597795(CHEMBL5191227)
Affinity DataIC50: 50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 73nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50515069(CHEMBL4522927 | US10899764, Example 28)
Affinity DataIC50: 85nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597799(CHEMBL5183213)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells in presence of heme measured after 20 hrs by heme-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597791(CHEMBL5188753)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597793(CHEMBL5182238)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597797(CHEMBL4459180)
Affinity DataIC50: 110nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562502(CHEMBL4749635)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant N-terminus 6-His tagged IDO1 expressed in Escherichia coli M15 incubated for 1 hr by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597782(CHEMBL5173772)
Affinity DataIC50: 111nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597796(CHEMBL5180495)
Affinity DataIC50: 200nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597801(CHEMBL5170610)
Affinity DataIC50: 240nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan incubated for 30 mins by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597788(CHEMBL5203360)
Affinity DataIC50: 250nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597800(CHEMBL5205177)
Affinity DataIC50: 300nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan as substrate incubated for 45 mins by SYNERGY-H1 microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 410nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50126145(CHEMBL3629570)
Affinity DataIC50: 468nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50597798(CHEMBL5202823)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562504(CHEMBL4794771)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50530532(CHEMBL4443463)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50126142(4-Phenylimidazole | CHEMBL14145 | US11053207, Comp...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM36371(CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...)
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of human recombinant His6-tagged IDO1 expressed in Escherichia coli strain BL21DE3pLysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataKi:  3.40E+4nMAssay Description:Binding affinity to IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed