Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50017968
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal His tagged PHD2 (181 to 426 residues) (unknown origin) measured by MALDI-TOF MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM107704(US8598210, Table XV, 11 | US8598210, 119 | US87228...)
Affinity DataIC50: 29nMAssay Description:Inhibition of N-terminal His tagged PHD2 (181 to 426 residues) (unknown origin) measured by MALDI-TOF MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606586(DAPRODUSTAT | Daprodustat | GSK-1278863 | GSK12788...)
Affinity DataIC50: 67nMAssay Description:Inhibition of N-terminal His tagged PHD2 (181 to 426 residues) (unknown origin) measured by MALDI-TOF MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606586(DAPRODUSTAT | Daprodustat | GSK-1278863 | GSK12788...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of FIH (unknown origin) by solid-phase extraction coupled to MS based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM107704(US8598210, Table XV, 11 | US8598210, 119 | US87228...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of FIH (unknown origin) by solid-phase extraction coupled to MS based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of FIH (unknown origin) assessed as hydroxylation of HIF1alphaCAD by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of FIH (unknown origin) by solid-phase extraction coupled to MS based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of FIH (unknown origin) assessed as hydroxylation of HIF1alphaCAD by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | L-2-Hydroxygluta...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of FIH (unknown origin) assessed as hydroxylation of HIF1alphaCAD by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed