Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50002692
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50098215(4-Amino-N-benzyl-2-[2-{3-[1-(2,6-dichloro-benzyl)-...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50098215(4-Amino-N-benzyl-2-[2-{3-[1-(2,6-dichloro-benzyl)-...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461680(CHEMBL4226439)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461681(Atopaxar | E-5555 | E5555 | ER-172594-00)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461680(CHEMBL4226439)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461681(Atopaxar | E-5555 | E5555 | ER-172594-00)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386391(CHEMBL1411333)
Affinity DataIC50: 199nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386391(CHEMBL1411333)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461684(CHEMBL4226980)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461684(CHEMBL4226980)
Affinity DataIC50: 316nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386408(CHEMBL2047297)
Affinity DataIC50: 970nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386408(CHEMBL2047297)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at PAR2 in human EAhy926 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386409(CHEMBL2047299)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461682(CHEMBL4226195)
Affinity DataIC50: 9.40E+4nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461683(CHEMBL4227184)
Affinity DataIC50: 9.99E+4nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461682(CHEMBL4226195)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461683(CHEMBL4227184)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed