Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002620
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460593(CHEMBL4228954)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460597(CHEMBL4225888)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50: 7.30nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460592(CHEMBL4225034)
Affinity DataIC50: 195nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460592(CHEMBL4225034)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460598(CHEMBL4226152)
Affinity DataIC50: 613nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460594(CHEMBL4225619)
Affinity DataIC50: 1.04E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460597(CHEMBL4225888)
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460593(CHEMBL4228954)
Affinity DataIC50: 4.68E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460595(CHEMBL4224776)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460596(CHEMBL4226403)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50460599(CHEMBL4225566)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed