Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50000311
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DGAT2 assessed as reduction in synthesis of triglycerol in human hepatocyte using [14C]glycerol as substrate preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human DGAT2 using [1-14C]decanoyl-CoA/1,2-didecanoyl-sn-glycerol as substrate preincubated for 120 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed
TargetCathepsin D(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)
Affinity DataIC50: 140nMAssay Description:Inhibition of cathepsin D (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed
TargetCathepsin D(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed