Compile Data Set for Download or QSAR
Report error Found 99 Enz. Inhib. hit(s) with all data for entry = 50046517
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391789(CHEMBL2146757)
Affinity DataIC50: 9nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116796(CHEMBL3612814)
Affinity DataIC50: 12nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116799(CHEMBL3612928)
Affinity DataIC50: 13nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat ROMK by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116799(CHEMBL3612928)
Affinity DataIC50: 16nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116799(CHEMBL3612928)
Affinity DataIC50: 16nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116795(CHEMBL3612807)
Affinity DataIC50: 18nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116798(CHEMBL3612926)
Affinity DataIC50: 24nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116798(CHEMBL3612926)
Affinity DataIC50: 24nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 27nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 32nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116829(CHEMBL3612796)
Affinity DataIC50: 35nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116798(CHEMBL3612926)
Affinity DataIC50: 40nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116843(CHEMBL3612811)
Affinity DataIC50: 43nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116843(CHEMBL3612811)
Affinity DataIC50: 43nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116801(CHEMBL3612806)
Affinity DataIC50: 49nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116797(CHEMBL3612924)
Affinity DataIC50: 54nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116827(CHEMBL3612798)
Affinity DataIC50: 60nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116840(CHEMBL3612813)
Affinity DataIC50: 61nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116840(CHEMBL3612813)
Affinity DataIC50: 61nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116796(CHEMBL3612814)
Affinity DataIC50: 64nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116796(CHEMBL3612814)
Affinity DataIC50: 64nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442600(CHEMBL2441437 | US9056859, 1)
Affinity DataIC50: 64nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116800(CHEMBL3612809)
Affinity DataIC50: 67nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116820(CHEMBL3612805)
Affinity DataIC50: 70nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391789(CHEMBL2146757)
Affinity DataIC50: 79nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116830(CHEMBL3612795)
Affinity DataIC50: 89nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391783(CHEMBL2146876)
Affinity DataIC50: 89nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116797(CHEMBL3612924)
Affinity DataIC50: 90nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116797(CHEMBL3612924)
Affinity DataIC50: 90nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116825(CHEMBL3612800)
Affinity DataIC50: 110nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116826(CHEMBL3612799)
Affinity DataIC50: 120nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116795(CHEMBL3612807)
Affinity DataIC50: 140nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116830(CHEMBL3612795)
Affinity DataIC50: 150nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116822(CHEMBL3612803)
Affinity DataIC50: 150nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116828(CHEMBL3612797)
Affinity DataIC50: 170nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116823(CHEMBL3612802)
Affinity DataIC50: 190nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116832(CHEMBL3612925)
Affinity DataIC50: 200nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116832(CHEMBL3612925)
Affinity DataIC50: 200nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116824(CHEMBL3612801)
Affinity DataIC50: 220nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391768(CHEMBL2146871 | US9073882, 95)
Affinity DataIC50: 300nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116821(CHEMBL3612804)
Affinity DataIC50: 300nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116833(CHEMBL3612923)
Affinity DataIC50: 340nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116833(CHEMBL3612923)
Affinity DataIC50: 340nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116848(CHEMBL3612808)
Affinity DataIC50: 410nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391768(CHEMBL2146871 | US9073882, 95)
Affinity DataIC50: 430nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116838(CHEMBL3612922)
Affinity DataIC50: 640nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116838(CHEMBL3612922)
Affinity DataIC50: 640nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116831(CHEMBL3612927)
Affinity DataIC50: 960nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116831(CHEMBL3612927)
Affinity DataIC50: 960nMAssay Description:Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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