Compile Data Set for Download or QSAR
Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 50040818
LigandPNGBDBM50400606(CHEMBL2203437)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400604(CHEMBL2203427)
Affinity DataKd:  1nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50310628(N-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenyl)i...)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50310628(N-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenyl)i...)
Affinity DataKd:  8.5nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1.57nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400613(CHEMBL2203429)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  1nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400613(CHEMBL2203429)
Affinity DataKd:  2nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400605(CHEMBL2203438)
Affinity DataKd:  1.28nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400605(CHEMBL2203438)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400612(CHEMBL2203430)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400606(CHEMBL2203437)
Affinity DataKd:  1.12nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400604(CHEMBL2203427)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400612(CHEMBL2203430)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400607(CHEMBL2203436)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400607(CHEMBL2203436)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400611(CHEMBL2203431)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400608(CHEMBL2203435)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400608(CHEMBL2203435)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400609(CHEMBL2203433)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400609(CHEMBL2203433)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400611(CHEMBL2203431)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400610(CHEMBL2203432)
Affinity DataKd:  3nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400610(CHEMBL2203432)
Affinity DataKd:  1nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to PDGFRalpha expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400614(CHEMBL2203426)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400614(CHEMBL2203426)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to PDGFRalpha expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataKd:  1nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400603(CHEMBL2203428)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400603(CHEMBL2203428)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to PDGFRalpha expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of KIT phosphorylation in human H526 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400600(CHEMBL2206277)
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400601(CHEMBL2203434)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of M-CSF-induced FK506 -fussed CSF1R phosphorylation expressed in HEK293 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400602(CHEMBL2206278)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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