Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50043527
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442473(CHEMBL2440368)
Affinity DataEC50:  4.60E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataEC50:  77nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataEC50:  120nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442487(CHEMBL2440370)
Affinity DataEC50:  620nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442474(CHEMBL2440367)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442478(CHEMBL2440376)
Affinity DataEC50:  3.70E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442477(CHEMBL2440378)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442475(CHEMBL2440366)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442472(CHEMBL2440369)
Affinity DataEC50:  2.10E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442488(CHEMBL2440374)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442488(CHEMBL2440374)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442487(CHEMBL2440370)
Affinity DataEC50:  2.90E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442486(CHEMBL2440381)
Affinity DataEC50:  3.30E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442476(CHEMBL2440365)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442479(CHEMBL2440371)
Affinity DataEC50:  3.50E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442472(CHEMBL2440369)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442486(CHEMBL2440381)
Affinity DataEC50:  4.70E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442485(CHEMBL2440372)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442484(CHEMBL2440373)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442483(CHEMBL2440375)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442482(CHEMBL2440377)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442481(CHEMBL2440379)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442480(CHEMBL2440380)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442479(CHEMBL2440371)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442478(CHEMBL2440376)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442477(CHEMBL2440378)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442476(CHEMBL2440365)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442475(CHEMBL2440366)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442474(CHEMBL2440367)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50442473(CHEMBL2440368)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed