Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50033438
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345359((2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 0.797nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345356((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-(t...)
Affinity DataIC50: 0.934nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345350((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(thiop...)
Affinity DataIC50: 1.18nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345353((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-(f...)
Affinity DataIC50: 1.24nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345344((2S,3R,4R,5S,6R)-2-(4-Chloro-2-methoxy-5-((5-(thio...)
Affinity DataIC50: 1.29nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345363((2S,3R,4R,5S,6R)-2-(4-Chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 1.51nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345354((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-(f...)
Affinity DataIC50: 1.54nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345343((2S,3R,4R,5S,6R)-2-(4-chloro-2-methoxy-5-((5-(thio...)
Affinity DataIC50: 1.59nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345355((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-(t...)
Affinity DataIC50: 1.69nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345345((2S,3R,4R,5S,6R)-2-(4-Chloro-2-methoxy-5-((5-pheny...)
Affinity DataIC50: 2.01nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345378((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5e((5-(thiop...)
Affinity DataIC50: 2.12nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345341((2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 2.15nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345361((2S,3R,4R,5S,6R)-2-(4-Chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 2.23nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345370((2S,3R,4R,5S,6R)-2-(4-chloro-2-(hydroxymethyl)-5-(...)
Affinity DataIC50: 2.23nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345381((2S,3R,4R,5S,6R)-2-(2,4-Dichloro-5-((5-(furan-2-yl...)
Affinity DataIC50: 2.24nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345384((2S,3R,4R,5S,6R)-2-(2,4-Dichloro-5-((5-(thiophen-3...)
Affinity DataIC50: 2.31nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345351((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-phenyl...)
Affinity DataIC50: 2.87nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345357((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-ph...)
Affinity DataIC50: 3.38nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345375((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5-((5-(furan...)
Affinity DataIC50: 3.49nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345377((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5-((5-(thiop...)
Affinity DataIC50: 3.88nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345347((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(furan...)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345358((2S,3R,4R,5S,6R)-2-(2-(Allyloxy)-4-chloro-5-((5-(4...)
Affinity DataIC50: 4.22nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345349((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(thiop...)
Affinity DataIC50: 4.29nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345348((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(furan...)
Affinity DataIC50: 4.35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345379((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5-((5-phenyl...)
Affinity DataIC50: 4.57nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345383((2S,3R,4R,5S,6R)-2-(2,4-Dichloro-5-((5-(thiophen-2...)
Affinity DataIC50: 4.77nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345376((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5-((5-(furan...)
Affinity DataIC50: 5.35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345364((2S,3R,4R,5S,6R)-2-(4-Chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 5.55nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345367((2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 5.81nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345369((2S,3R,4R,5S,6R)-2-(4-chloro-2-(hydroxymethyl)-5-(...)
Affinity DataIC50: 5.88nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345346((2S,3R,4R,5S,6R)-2-(4-Chloro-5-((5-(4-fluorophenyl...)
Affinity DataIC50: 6.08nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345342((2S,3R,4R,5S,6R)-2-(4-Chloro-5-((5-(furan-3-yl)thi...)
Affinity DataIC50: 7.37nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345352((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5e((5-(4-flu...)
Affinity DataIC50: 7.55nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345374((2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345382((2S,3R,4R,5S,6R)-2-(2,4-Dichloro-5-((5-(furan-3-yl...)
Affinity DataIC50: 13.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345373((2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-...)
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345371((2S,3R,4R,5S,6R)-2-(2-(allyloxymethyl)-4-chloro-5-...)
Affinity DataIC50: 17.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345368((2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-3-yl)thi...)
Affinity DataIC50: 20.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345360((2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-2-yl)thi...)
Affinity DataIC50: 21.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345380((2S,3R,4R,5S,6R)-2-(4-Chloro-2-fluoro-5-((5-(4-flu...)
Affinity DataIC50: 27.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345362((2S,3R,4R,5S,6R)-2-(2-(But-3-enyloxy)-4-chloro-5-(...)
Affinity DataIC50: 32.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345372((2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-...)
Affinity DataIC50: 38.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345365((2S,3R,4R,5S,6R)-2-(2-(2-(1H-1,2,4-triazol-1-yl)et...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345366((2S,3R,4R,5S,6R)-2-(4-chloro-2-(2-(dimethylamino)e...)
Affinity DataIC50: 713nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed