Compile Data Set for Download or QSAR
Report error Found 179 Enz. Inhib. hit(s) with all data for entry = 50039071
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308898(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14028(H-1152 | 4-methyl-5-{[(2S)-2-methyl-1,4-diazepane-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308862(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308858(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308897(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308876(3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308859(3-[3-(3-Chloro-4-cyano-phenyl)-ureidomethyl]-N-(3-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308875(3,4-Dimethoxy-N-[3-(2-methyl-1,2,3,4-tetrahydro-is...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308862(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308872(3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoy...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human ROCK2 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308900(3,4-Dimethoxy-N-[3-(3-piperidin-3-yl-propionylamin...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308894(3-[3-(3-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308872(3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoy...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308877(3,4-Dimethoxy-N-[3-(2-piperidin-4-yl-ethylcarbamoy...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308860(N-(4-Aminomethyl-phenyl)-3-[3-(4-cyano-phenyl)-ure...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308873(3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308865(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308867(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308867(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308898(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 770nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 780nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308899(N-[3-(4-Hydroxymethyl-phenylcarbamoyl)-benzyl]-3,4...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308879(rac-3,4-dimethoxy-N-(3-((tetrahydrofuran-2-yl)meth...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308864(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308862(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308875(3,4-Dimethoxy-N-[3-(2-methyl-1,2,3,4-tetrahydro-is...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human CYP3A4 using BFC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308897(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308898(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PRKG1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308898(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308881(rac-3-((3-(3-cyanophenyl)ureido)methyl)-N-((tetrah...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308872(3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoy...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308878(3,4-dimethoxy-N-(3-(propylcarbamoyl)benzyl)benzami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308875(3,4-Dimethoxy-N-[3-(2-methyl-1,2,3,4-tetrahydro-is...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308876(3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308872(3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308877(3,4-Dimethoxy-N-[3-(2-piperidin-4-yl-ethylcarbamoy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
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