Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50030351
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataEC50:  1.23nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataEC50:  41.2nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataEC50:  0.140nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataEC50:  10.4nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  8.53nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  209nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273938((S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  0.825nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273996((S)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  0.920nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294841((4-{2-[(7-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  1.67nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294848(Benzo[b]thiophen-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-te...)
Affinity DataKi:  1.69nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273937((R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  1.77nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294842(7-((2-(4-(1H-indol-5-yl)piperazin-1-yl)ethyl)(prop...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  2.27nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294846((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  2.83nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294845((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  3.62nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294838((4-{2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  3.72nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294840(7-({2-[4-(1H-Indol-5-ylmethyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  3.87nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294839(7-({2-[4-(1H-Indol-2-ylmethyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  4.82nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294849((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  5.18nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294847(Benzofuran-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahyd...)
Affinity DataKi:  5.23nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020222(CHEMBL285755 | 7-Dipropylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  6.19nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273938((S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294846((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294842(7-((2-(4-(1H-indol-5-yl)piperazin-1-yl)ethyl)(prop...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273937((R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  40.6nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  47.5nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  47.5nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294844((+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  51.2nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataKi:  58.8nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294845((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  58.9nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294841((4-{2-[(7-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  65.9nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294848(Benzo[b]thiophen-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-te...)
Affinity DataKi:  76.9nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294839(7-({2-[4-(1H-Indol-2-ylmethyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294838((4-{2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294847(Benzofuran-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahyd...)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294840(7-({2-[4-(1H-Indol-5-ylmethyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294849((4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50273996((S)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  264nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020222(CHEMBL285755 | 7-Dipropylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  311nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed