Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 2835
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DatapH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 26nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 43nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25142((3S,6S,9S,15aR)-9-[(2R)-butan-2-yl]-6-[(1-methoxy-...)
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 48nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 55nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 57nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 59nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 59nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 82nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25145((2S)-8-oxo-2-[3-(piperidin-1-yl)propanamido]-N-(qu...)
Affinity DataIC50: 140nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 340nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 400nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 540nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25147(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Affinity DataIC50: 670nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25147(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Affinity DataIC50: 880nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: 970nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25147(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.70E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 4 [653-1084,H976Y](Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: 4.20E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 5.00E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25147(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25148(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25147(N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2008
Entry Details Article
PubMed