Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 2036
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16274(CHEMBL425483 | 2-({2-[(3R)-3-aminopiperidin-1-yl]-...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16281(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-fluoro-6-meth...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16273(2-({2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-4-oxo-...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16275(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-chloro-4-oxo-...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16279(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-bromo-4-oxo-3...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16280(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-methoxy-4-oxo...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16272(Racemic | 2-({2-[(3R)-3-aminopiperidin-1-yl]-4-oxo...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16278(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,8-dichloro-4-...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16276(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-chloro-4-oxo-...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16284(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-7-(mor...)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16282(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxy-4...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16277(Racemic | 2-({2-[(3R)-3-aminopiperidin-1-yl]-8-chl...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

LigandPNGBDBM16283(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-methoxy-4-oxo...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16284(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-7-(mor...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16275(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-chloro-4-oxo-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16280(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-methoxy-4-oxo...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16283(2-({2-[(3R)-3-aminopiperidin-1-yl]-8-methoxy-4-oxo...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16282(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxy-4...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16281(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-fluoro-6-meth...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16279(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-bromo-4-oxo-3...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16278(2-({2-[(3R)-3-aminopiperidin-1-yl]-6,8-dichloro-4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16277(Racemic | 2-({2-[(3R)-3-aminopiperidin-1-yl]-8-chl...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16276(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-chloro-4-oxo-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16274(CHEMBL425483 | 2-({2-[(3R)-3-aminopiperidin-1-yl]-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16273(2-({2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-4-oxo-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

LigandPNGBDBM16272(Racemic | 2-({2-[(3R)-3-aminopiperidin-1-yl]-4-oxo...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
PubMed