Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 2083
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16679(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16688(N-[(2S,3R)-3-amino-4-methoxy-1-phenylbutan-2-yl]-2...)
Affinity DataIC50: 6nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16676(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50: 9nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16680(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50: 11nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16685(N-[(2S,3R)-3-amino-4-methoxy-1-phenylbutan-2-yl]-2...)
Affinity DataIC50: 12nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16675(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50: 13nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16678(N-[(2S,3S)-3-amino-1-phenylheptan-2-yl]-2-({[(1S,2...)
Affinity DataIC50: 20nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16686(N-[(2S,3R)-3-amino-4-methoxy-1-phenylbutan-2-yl]-2...)
Affinity DataIC50: 24nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16687(N-[(2S,3R)-3-amino-4-ethoxy-1-phenylbutan-2-yl]-2-...)
Affinity DataIC50: 24nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16682(N-[(2S,3S)-3-amino-1-phenylheptan-2-yl]-2-[methyl(...)
Affinity DataIC50: 31nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16681(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50: 32nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16677(N-[(2S)-1-amino-3-phenylpropan-2-yl]-2-({[(1S,2S)-...)
Affinity DataIC50: 34nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16683(N-[(2S,3S)-3-amino-1-phenylheptan-2-yl]-2-[methyl(...)
Affinity DataIC50: 39nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16684(N-[(2S,3S)-3-amino-1-phenylbutan-2-yl]-2-[methyl({...)
Affinity DataIC50: 67nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16674(N-[(2S)-1-(3,5-difluorophenyl)-3-hydroxypropan-2-y...)
Affinity DataIC50: 74nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed