Report error Found 113 of ic50 data for polymerid = 9822
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human N-terminal polyhis-tagged SIRT6 (1 to 355 residues) defatty-acylase activity expressed in Escherichia coli using SFP3...More data for this Ligand-Target Pair
Affinity DataIC50: 256nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 368nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 495nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of sirtuin 6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human SIRT6 using H3K9 myristoyl-peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human SIRT6 using H3K9 myristoyl-peptide substrateMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-SIRT6 (unknown origin) assessed as deacetylation reaction using calf thymus histone as substrate by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-tagged SIRT6 (unknown origin) deacetylase activity using H3K9Ac peptide substrate by reversed-phase HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human SIRT6 (1 to 294 residues) expressed in Escherichia coli Rosetta (DE3) using H3K9AcWW as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of sirtuin 6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of GST-tagged SIRT6 (unknown origin) deacetylase activity using H3K9Ac peptide substrate by reversed-phase HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of GST-SIRT6 (unknown origin) assessed as deacetylation reaction demyristoylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of demyristoylation activity of recombinant human full length N-terminal His6-tagged SIRT6 expressed in Escherichia coli using H2N-EALPK-[...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human SIRT6 using H3K9 myristoyl-peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.09E+3nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.46E+3nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of demyristoylation activity of recombinant human full length N-terminal His6-tagged SIRT6 expressed in Escherichia coli using H2N-EALPK-[...More data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human SIRT6 (1 to 294 residues) expressed in Escherichia coli Rosetta (DE3) using H3K9AcWW as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human SIRT6 (1 to 294 residues) expressed in Escherichia coli Rosetta (DE3) using H3K9AcWW as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of His-tagged human SIRT6 expressed in Escherichia coli BL21(DE3) using Ac-p53 as substrate by fluorescence-based coupled-enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of human SIRT6 using labeled peptide Acp53 (Ac-Arg-His-Lys-Lys (Ac)-AMC) substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of SIRT6 (unknown origin) using Ac-RYQK(Ac)-AMC as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...More data for this Ligand-Target Pair
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human SIRT6 demyristoylation reaction assessed as deacylation using H3K9 decanoyl peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation after 90 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assayMore data for this Ligand-Target Pair
