Compile Data Set for Download or QSAR
Report error Found 64 of ic50 data for polymerid = 963
TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515356(US11098060, Example 14 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 0.120nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515377(US11098060, Example 37 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 0.210nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515357(US11098060, Example 15 | (13E,14E,22R,24S,5S)-12-a...)
Affinity DataIC50: 0.220nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515375(US11098060, Example 35 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 0.360nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515361(US11098060, Example 19 | (13E,14E,22R,24S,6R)-12-a...)
Affinity DataIC50: 0.380nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515360(US11098060, Example 18 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 0.400nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515372(US11098060, Example 32 | (13E,14E,22R,5S)-12-amino...)
Affinity DataIC50: 0.430nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647638(US20240025908, Example 6 | T-12)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647642(US20240025908, Example 10 | T-42)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647641(US20240025908, Example 9 | T-37)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647640(US20240025908, Example 8 | T-36)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647635(US20240025908, Example 3 | T-05)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647639(US20240025908, Example 7 | T-17)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515358(US11098060, Example 16 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 0.550nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515354(US11098060, Example 34 | US11098060, Example 12)
Affinity DataIC50: 0.820nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515354(US11098060, Example 34 | US11098060, Example 12)
Affinity DataIC50: 0.880nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472735(2-amino-5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-...)
Affinity DataIC50: 1nMAssay Description:TrkAG667C: TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells (purchased from Invitrogen) using pIEX-Bac-4 (purchased from Merck), and purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515367(US11098060, Example 26)
Affinity DataIC50: 1.22nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515373(US11098060, Example 33 | (R,13E,14E)-12-amino-35-f...)
Affinity DataIC50: 1.46nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515350(US11098060, Example 8 | (R,13E,14E)-12-amino-35-fl...)
Affinity DataIC50: 1.63nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515345(US11098060, Example 1)
Affinity DataIC50: 1.68nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515363(US11098060, Example 21)
Affinity DataIC50: 1.71nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515346(US11098060, Example 2 | (13E,14E)-12-amino-35-fluo...)
Affinity DataIC50: 1.86nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515368(US11098060, Example 27 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 1.89nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515365(US11098060, Example 23)
Affinity DataIC50: 2.39nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515352(US11098060, Example 10 | (R,13E,14E)-12-amino-35-f...)
Affinity DataIC50: 2.41nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515371(US11098060, Example 31 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 2.43nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647653(US20240025908, Example 21)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647658(US20240025908, Example 26)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647636(US20240025908, Example 4 | T-07)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647634(US20240025908, Example 2 | T-02)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647633(US20240025908, Example 1 | T-01)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647657(US20240025908, Example 25)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647655(US20240025908, Example 23)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647652(US20240025908, Example 20)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM647654(US20240025908, Example 22)
Affinity DataIC50: 2.75nMAssay Description:Inhibition of protein kinase activity by compounds was carried out on the Radio-tagged HotSpot kinase experimental platform of Reaction Biology Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515370(US11098060, Example 29 | (13E,14E,22R,24S,6S)-12-a...)
Affinity DataIC50: 3.16nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515349(US11098060, Example 6 | (R,13E,14E)-12-amino-4-oxa...)
Affinity DataIC50: 5.61nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515351(US11098060, Example 9 | (13E,14E,22R,24R)-12-amino...)
Affinity DataIC50: 5.74nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515359(US11098060, Example 17 | (13E,14E,22R,24S)-12-amin...)
Affinity DataIC50: 8.07nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515376(US11098060, Example 36 | (13E,14E,22R,24R)-12-amin...)
Affinity DataIC50: 8.16nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472759(2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...)
Affinity DataIC50: 10nMAssay Description:TrkAG667C: TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells (purchased from Invitrogen) using pIEX-Bac-4 (purchased from Merck), and purif...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472762(2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...)
Affinity DataIC50: 10nMAssay Description:TrkAG667C: TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells (purchased from Invitrogen) using pIEX-Bac-4 (purchased from Merck), and purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515348(US11098060, Example 5 | (R,13E,14E)-12-amino-4-oxa...)
Affinity DataIC50: 12.1nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515364(US11098060, Example 22)
Affinity DataIC50: 12.8nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515369(US11098060, Example 28 | (13E,14E,22R,6R)-12-amino...)
Affinity DataIC50: 13.4nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515355(US11098060, Example 13 | (13E,14E, 22R,24R)-12-ami...)
Affinity DataIC50: 14.6nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515362(US11098060, Example 20)
Affinity DataIC50: 15.1nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515366(US11098060, Example 24 | (13E,14E)-12-amino-35-flu...)
Affinity DataIC50: 16nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515347(US11098060, Example 3 | (13E,14E)-12-amino-4-oxa-8...)
Affinity DataIC50: 16.2nMAssay Description:TrkAG667C (Kinase domain) kinase was expressed in Sf9 cells by using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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