Compile Data Set for Download or QSAR
Report error Found 31 of ic50 data for polymerid = 9297,49000396
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50078048(1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Ni...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50329578((-)-9-Bromocytisine | (1R,5S)-9-Bromo-1,2,3,4,5,6-...)
Affinity DataIC50: 15.6nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Ni...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50487992(CHEMBL2270633)
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Ni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50416397(CHEMBL1210515)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296747(3-benzoyl-4-bromophenyl 1,4-diazabicyclo[3.2.2]non...)
Affinity DataIC50: 1.39E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296743(4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nona...)
Affinity DataIC50: 2.09E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50406134(CHEMBL5275403)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50406130(CHEMBL5272946)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataIC50: 3.25E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296744(4-bromo-3-methylphenyl 1,4-diazabicyclo[3.2.2]nona...)
Affinity DataIC50: 4.02E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296745(3,4-dichlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4...)
Affinity DataIC50: 4.75E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296748(naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-ca...)
Affinity DataIC50: 4.91E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296727(4-chlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-car...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296742(1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl car...)
Affinity DataIC50: 6.48E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataIC50: 7.94E+3nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50296746(4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]non...)
Affinity DataIC50: 9.96E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50: 1.16E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50212288((2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimida...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Ni...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50: 3.16E+4nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241747(3-demethoxy-2alpha,3alpha-methylenedioxyerythrocul...)
Affinity DataIC50: 7.70E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha-3-beta-4R2 cells assessed as nicotine-induced calcium fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241746(15-amido-3-demethoxy-2alpha,3alpha-methylenedioxye...)
Affinity DataIC50: 9.40E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha-3-beta-4R2 cells assessed as nicotine-induced calcium fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241748(dihydro-beta-erythroidine | CHEMBL518059)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha-3-beta-4R2 cells assessed as nicotine-induced 86Rb+ effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed