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TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM217355(4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...)
Affinity DataIC50: 63nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676514(US20240166642, Example 6b)
Affinity DataIC50: 300nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676522(US20240166642, Example 12b)
Affinity DataIC50: 320nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676510(US20240166642, Example 4a)
Affinity DataIC50: 370nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676538(US20240166642, Example 23)
Affinity DataIC50: 380nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676532(US20240166642, Example 18b)
Affinity DataIC50: 410nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676513(US20240166642, Example 6a)
Affinity DataIC50: 420nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676519(US20240166642, Example 10b)
Affinity DataIC50: 430nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676524(US20240166642, Example 13b)
Affinity DataIC50: 430nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676520(US20240166642, Example 11)
Affinity DataIC50: 540nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676525(US20240166642, Example 14)
Affinity DataIC50: 540nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676526(US20240166642, Example 15)
Affinity DataIC50: 540nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676536(US20240166642, Example 21)
Affinity DataIC50: 540nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676544(US20240166642, Example 29)
Affinity DataIC50: 540nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676507(US20240166642, Example 2b)
Affinity DataIC50: 550nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676508(US20240166642, Example 3a)
Affinity DataIC50: 550nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676539(US20240166642, Example 24)
Affinity DataIC50: 560nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676534(US20240166642, Example 19b)
Affinity DataIC50: 570nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676540(US20240166642, Example 25)
Affinity DataIC50: 570nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM92467(2-Thioxanthine, TX2)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676545(US20240166642, Example 30)
Affinity DataIC50: 590nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676515(US20240166642, Example 7)
Affinity DataIC50: 610nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676530(US20240166642, Example 17b)
Affinity DataIC50: 630nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567713(CHEMBL4859908)
Affinity DataIC50: 640nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676521(US20240166642, Example 12a)
Affinity DataIC50: 670nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676542(US20240166642, Example 27)
Affinity DataIC50: 670nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676543(US20240166642, Example 28)
Affinity DataIC50: 680nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567712(CHEMBL4869433)
Affinity DataIC50: 700nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676509(US20240166642, Example 3b)
Affinity DataIC50: 700nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567715(CHEMBL4855931)
Affinity DataIC50: 710nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676531(US20240166642, Example 18a)
Affinity DataIC50: 730nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676529(US20240166642, Example 17a)
Affinity DataIC50: 760nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50595667(CHEMBL5181350)
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676528(US20240166642, Example 16b)
Affinity DataIC50: 780nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676511(US20240166642, Example 4b)
Affinity DataIC50: 810nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676541(US20240166642, Example 26)
Affinity DataIC50: 840nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676505(US20240166642, Example 1b)
Affinity DataIC50: 850nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM312172(Alternative Preparation | US9616063, 3 | US1001643...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676516(US20240166642, Example 8)
Affinity DataIC50: 930nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676537(US20240166642, Example 22)
Affinity DataIC50: 950nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50133595(CHEMBL3633460)
Affinity DataIC50: 990nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676504(US20240166642, Example 1a)
Affinity DataIC50: 1.01E+3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676506(US20240166642, Example 2a)
Affinity DataIC50: 1.04E+3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676523(US20240166642, Example 13a)
Affinity DataIC50: 1.05E+3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567717(CHEMBL4853722)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567718(CHEMBL4863015)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50567722(CHEMBL4862053)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM50595666(CHEMBL5200126)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM312173(1-{2-[(1S)-1-Aminoethyl]-4-chlorobenzyl}-2-thioxo-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetThyroid peroxidase(Human)
University of Otago Christchurch

LigandPNGBDBM676518(US20240166642, Example 10a)
Affinity DataIC50: 1.20E+3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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