Compile Data Set for Download or QSAR
Report error Found 1004 of ic50 data for polymerid = 8592,50002253,50006794,50007446
TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616687(US20230278998, Compound 5)
Affinity DataIC50: 0.5nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616699(US20230278998, Compound 17)
Affinity DataIC50: 0.600nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616700(US20230278998, Compound 18)
Affinity DataIC50: 0.900nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616727(US20230278998, Compound 46)
Affinity DataIC50: 0.900nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616685(US20230278998, Compound 3)
Affinity DataIC50: 1nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616694(US20230278998, Comparative Compound 1' | US2023030...)
Affinity DataIC50: 1.90nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM616747(US20230278998, Comparative Compound 2')
Affinity DataIC50: 2.30nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658634(US20240083908, Example 130)
Affinity DataIC50: 3nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371055(US10239843, Example 162)
Affinity DataIC50: 4nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658612(US20240083908, Example 108)
Affinity DataIC50: 4nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658542(US20240083908, Example 38)
Affinity DataIC50: 4.10nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658544(US20240083908, Example 40)
Affinity DataIC50: 4.10nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658540(US20240083908, Example 36)
Affinity DataIC50: 5.30nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371063(US10239843, Example 170)
Affinity DataIC50: 6nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371355(US10239843, Example 463 | 1-[(2,4-Dimethylthiazol-...)
Affinity DataIC50: 6nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658635(US20240083908, Example 131)
Affinity DataIC50: 6.30nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371463(US10239843, Example 572 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 7nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371294(US10239843, Example 401 | N-(1-Cyanocyclopropyl)-1...)
Affinity DataIC50: 8nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371454(US10239843, Example 563 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 8nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371470(US10239843, Example 579 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 9nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658541(US20240083908, Example 37)
Affinity DataIC50: 9nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658550(US20240083908, Example 46)
Affinity DataIC50: 9.20nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658516(US20240083908, Example 12)
Affinity DataIC50: 9.90nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371469(US10239843, Example 578 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 10nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658532(US20240083908, Example 28)
Affinity DataIC50: 10nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371267(US10239843, Example 374)
Affinity DataIC50: 11nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371289(US10239843, Example 396 | 1-[(2,4-Dimethylthiazol-...)
Affinity DataIC50: 11nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658508(US20240083908, Example 4)
Affinity DataIC50: 11nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658565(US20240083908, Example 61)
Affinity DataIC50: 11nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371056(US10239843, Example 163)
Affinity DataIC50: 12nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658509(US20240083908, Example 5)
Affinity DataIC50: 12nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658529(US20240083908, Example 25)
Affinity DataIC50: 13nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658549(US20240083908, Example 45)
Affinity DataIC50: 13nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658593(US20240083908, Example 89)
Affinity DataIC50: 13nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658510(US20240083908, Example 6)
Affinity DataIC50: 14nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658568(US20240083908, Example 64)
Affinity DataIC50: 15nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658620(US20240083908, Example 116)
Affinity DataIC50: 15nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371519(N-[1-(Fluoromethyl)cyclopropyl]-1-[(1-methylpyrazo...)
Affinity DataIC50: 16nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658514(US20240083908, Example 10)
Affinity DataIC50: 16nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371506(1-[(2,4-Dimethylthiazol-5-yl)methyl]-N-[1-(fluorom...)
Affinity DataIC50: 17nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658577(US20240083908, Example 73)
Affinity DataIC50: 17nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658594(US20240083908, Example 90)
Affinity DataIC50: 17nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658614(US20240083908, Example 110)
Affinity DataIC50: 17nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM658626(US20240083908, Example 122)
Affinity DataIC50: 17nMAssay Description:PARG Activity Assay was performed in Streptavidin-coated 96-well plates. Terminal-biotinylated poly (ADP-ribose) polymer was diluted to a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371066(US10239843, Example 173)
Affinity DataIC50: 18nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371049(US10239843, Example 156)
Affinity DataIC50: 19nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371479(US10239843, Example 588 | N-[1-(Fluoromethyl)cyclo...)
Affinity DataIC50: 19nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM371268(US10239843, Example 375)
Affinity DataIC50: 20nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM50508415(CHEMBL4459798)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
280 Bio

US Patent
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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