BindingDB PrimarySearch

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

72 kDa type IV collagenase(Mouse)
University of Montreal

Curated by ChEMBL

BDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)

IC50: 4.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199123(N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-tri...)

IC50: 8.12nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

72 kDa type IV collagenase(Mouse)
University of Montreal

Curated by ChEMBL

BDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)

IC50: 15nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair

Purchase CHEMBL DrugBank PC cid PC sid

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199124(N-(4-(1-(4,6-bis((4-methoxyphenyl)amino)-1,3,5-tri...)

IC50: 18.6nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199128(N-(4-(1-(4,6-dimorpholino-1,3,5-triazin-2-yl)-5-(4...)

IC50: 42.3nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199127(N-(4-(1-(4,6-di(piperazin-1-yl)-1,3,5-triazin-2-yl...)

IC50: 55.3nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199125(N-(4-(1-(4,6-bis(o-tolylamino)-1,3,5-triazin-2-yl)...)

IC50: 67.1nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199126(N-(4-(1-(4,6-bis((4-nitrophenyl)amino)-1,3,5-triaz...)

IC50: 76.6nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199122(N-(4-(1-(4,6-bis(phenylamino)-1,3,5-triazin-2-yl)-...)

IC50: 123nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199121(N-(4-(1-(4,6-bis((3-aminopropyl)amino)-1,3,5-triaz...)

IC50: 189nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199120(N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5...)

IC50: 332nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM199119(N-(4-(1-(4,6-bis(methylamino)-1,3,5-triazin-2-yl)-...)

IC50: 666nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310832(Clinopodic acid C | CHEMBL1080779)

IC50: 3.26E+3nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50250808(lithospermic acid | CHEMBL518243)

IC50: 1.02E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

Purchase CHEMBL KEGG PC cid PC sid

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50133496(Rosmarinic acid, 2 | cid_5281792 | CHEMBL324842 | ...)

IC50: 2.72E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

Purchase CHEMBL KEGG PC cid PC sid PDB

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240824((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 6.46E+4nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310827(clinopodic acid H | CHEMBL1079357)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310828(clinopodic acid F | CHEMBL1079356)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310829(clinopodic acid E | CHEMBL1081512)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310830(Clinopodic acid B | CHEMBL1080778)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50310831(Clinopodic acid A | CHEMBL1079231)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

72 kDa type IV collagenase(Rat)
Zhejiang Hospital

BDBM50210054(3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(3,4-dihyd...)

IC50: 1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240825((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 1.28E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)

IC50: 1.63E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240822((S)-2-((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpr...)

IC50: 1.86E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240827((2S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanam...)

IC50: 2.07E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240828((2R,3S)-3-amino-2-hydroxy-N-((S)-2-(hydroxyamino)-...)

IC50: 2.13E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240812((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 2.15E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240829((2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-...)

IC50: 2.49E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240816((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 2.54E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240815((2S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanam...)

IC50: 2.64E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240814((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 2.73E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240813((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 2.87E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240826((2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-...)

IC50: 2.92E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240831((2R,3S)-3-amino-2-hydroxy-N-((S)-3-hydroxy-1-(hydr...)

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240830((2R,3S)-3-amino-2-hydroxy-N-((S)-1-(hydroxyamino)-...)

IC50: 2.99E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240818((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 4.07E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240821((S)-2-((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpr...)

IC50: 4.24E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240817((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 4.97E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240819((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpropanami...)

IC50: 5.62E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair

72 kDa type IV collagenase(Pig)
Shandong University

BDBM240820((S)-2-((S)-2-((2R,3S)-3-amino-2-hydroxy-3-phenylpr...)

IC50: 6.90E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair