Compile Data Set for Download or QSAR
Report error Found 2539 of ic50 data for polymerid = 7531,9757,50001157
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50506874(CHEMBL4161103)
Affinity DataIC50: 0.0300nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50570217(CHEMBL4863423)
Affinity DataIC50: 0.0400nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514163(CHEMBL4568985)
Affinity DataIC50: 0.0700nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 0.220nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 0.260nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50567579(Encequidar | Pgp inhibitor hm30181ak | HM-30181 | ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of paclitaxel stimulated- P-gp ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514163(CHEMBL4568985)
Affinity DataIC50: 0.640nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 0.660nMAssay Description:Inhibition of human ABCB1 expressed in KBV1 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 1000 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 0.710nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514158(CHEMBL4526913)
Affinity DataIC50: 0.780nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50570217(CHEMBL4863423)
Affinity DataIC50: 0.790nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50570217(CHEMBL4863423)
Affinity DataIC50: 0.890nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50238974(CHEMBL4085670)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50621805(CHEMBL5429850)
Affinity DataIC50: 1.40nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50506874(CHEMBL4161103)
Affinity DataIC50: 1.5nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50201796(CHEBI:5677 | Hernandezine)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human ABCB1 expressed in KBV1 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 500 n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50581481(CHEMBL5089855)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of P-glycoprotein in human LCC6MDR cells assessed as reversal fold by measuring reduction in paclitaxel by measuring paclitaxel IC50 at 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514163(CHEMBL4568985)
Affinity DataIC50: 1.90nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514161(CHEMBL4469705)
Affinity DataIC50: 2nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 2.10nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50621799(CHEMBL5439145)
Affinity DataIC50: 2.10nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50506874(CHEMBL4161103)
Affinity DataIC50: 2.20nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50581480(CHEMBL5088809)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of P-glycoprotein in human LCC6MDR cells assessed as reversal fold by measuring reduction in paclitaxel by measuring paclitaxel IC50 at 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50621802(CHEMBL5408118)
Affinity DataIC50: 2.30nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50506874(CHEMBL4161103)
Affinity DataIC50: 2.40nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50091138(CHEMBL3582168)
Affinity DataIC50: 2.70nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514158(CHEMBL4526913)
Affinity DataIC50: 2.90nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50091264(CHEMBL3582155)
Affinity DataIC50: 3nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 3nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50238973(CHEMBL4064097)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50091087(CHEMBL3582156)
Affinity DataIC50: 3.30nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 3.30nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 3.30nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of P-gp in human CEM cells incubated for 15 mins by calcein-AM efflux methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50109277(CHEMBL3601686)
Affinity DataIC50: 3.5nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50621798(CHEMBL5403208)
Affinity DataIC50: 3.5nMAssay Description:Negative allosteric modulator activity at human P-gp G1114V mutant expressed in HEK293FT cells assessed as reversal of P-gp mediated PTX resistance b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50091265(CHEMBL3582149)
Affinity DataIC50: 3.70nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50621798(CHEMBL5403208)
Affinity DataIC50: 3.80nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50238970(CHEMBL4094336)
Affinity DataIC50: 4nMAssay Description:Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50514160(CHEMBL4557604)
Affinity DataIC50: 4nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50: 4nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 2539 total ) | Next | Last >>
Jump to: