Compile Data Set for Download or QSAR
Report error Found 185 of ic50 data for polymerid = 7527
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50390979(BROMOSULFOPHTHALEIN)
Affinity DataIC50: 50nMAssay Description:TP_TRANSPORTER: inhibition of Phalloidin uptake (Phalloidin: 1 uM) in OATP-C-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50458163(CHEMBL4209316)
Affinity DataIC50: 66nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50586032(CHEMBL5077187)
Affinity DataIC50: 100nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442899(CHEMBL1491099)
Affinity DataIC50: 102nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442896(CHEMBL1328088)
Affinity DataIC50: 145nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50581550(Bms-986020 | AP-3152 FREE ACID | BMS-986020)
Affinity DataIC50: 170nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)
Affinity DataIC50: 180nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using [3H]estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 230nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442865(Sarsasapogenin)
Affinity DataIC50: 245nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 280nMAssay Description:Inhibition of human OATP1B1-mediated [3H]estrone 3-sulfate at after 5 mins by Dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 288nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50370232(BA-41166E | L-5103 | Rifadin | Rifampicin | RIFAMP...)
Affinity DataIC50: 300nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50380880(CHEMBL2018969)
Affinity DataIC50: 398nMAssay Description:Antagonist activity at OATP1B1 (unknown origin) by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM172715(US9090657, DEBIO-025, 2)
Affinity DataIC50: 450nMpH: 7.3 T: 2°CAssay Description:To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM79589(cid_6426773 | MLS001304052 | SMR000538906 | LASALO...)
Affinity DataIC50: 479nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataIC50: 525nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 600nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50581556(CHEMBL5085260)
Affinity DataIC50: 600nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM22319([1-14C]Arachidonic acid | (5Z,8Z,11Z,14Z)-icosa-5,...)
Affinity DataIC50: 603nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM54988(cid_5280489 | beta;-Carotene | SMR000112037 | MLS0...)
Affinity DataIC50: 617nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50005106(Pathocil | P-1011 | CHEBI:52019 | Dycill | BRL-170...)
Affinity DataIC50: 676nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442889(CHEMBL3039300)
Affinity DataIC50: 676nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50553286(CHEMBL4794465)
Affinity DataIC50: 690nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442903(CHEMBL3039411)
Affinity DataIC50: 692nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 700nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 700nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 700nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50318907(CHEMBL1014 | TCV-116 | candesartancilexetil | Atac...)
Affinity DataIC50: 724nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataIC50: 724nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 750nMAssay Description:Inhibition of OATP1B1 (unknown origin) mediated [3H]-estrone sulfate uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442888(CHEMBL3039293)
Affinity DataIC50: 759nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)
Affinity DataIC50: 800nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in CHO cells using 8-fluorescein-cAMP substrate by fluorescent photometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442898(CHEMBL3138689)
Affinity DataIC50: 813nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442868(Atorvastatin | Atorvastatin Calcium)
Affinity DataIC50: 813nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataIC50: 813nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM172718(US9090657, Cyclosporine A, 1 | US11802108, Compoun...)
Affinity DataIC50: 850nMpH: 7.3 T: 2°CAssay Description:To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM22164(CI 981 | CHEMBL1487 | (3R,5R)-7-[2-(4-fluorophenyl...)
Affinity DataIC50: 870nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442883(CHEMBL3138678)
Affinity DataIC50: 871nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442872(CHEMBL3138660)
Affinity DataIC50: 933nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442902(CHEMBL3138712)
Affinity DataIC50: 977nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50442892(CS-866 | Benicar | OLMESARTAN MEDOXOMIL)
Affinity DataIC50: 977nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50030555(CHEMBL3344493 | US9566312, Compound 2.10)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in CHO cells using 8-fluorescein-cAMP substrate by fluorescent photometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using pitavastatin substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50485551(Antamanide)
Affinity DataIC50: 1.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of Phalloidin uptake (Phalloidin: 1 uM) in OATP-C-expressing HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM138224(US8871738, 62 | US8871738, 7)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM138278(US8871738, 61)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM138252(US8871738, 35)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM138290(US8871738, 73)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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