Compile Data Set for Download or QSAR
Report error Found 214 of ic50 data for polymerid = 730,2421,50003271
TargetEquilibrative nucleoside transporter 1(Rat)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ENT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50301066(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412033(CHEMBL260688)
Affinity DataIC50: 2.75nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036307(CHEMBL3353069)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036309(CHEMBL3353072)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036311(CHEMBL3353074)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412008(CHEMBL259866)
Affinity DataIC50: 4.79nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50301067(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50376975(CHEMBL260570)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.430nM ΔG°:  -52.9kJ/mole IC50: 7.60nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 8.51nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23631(2-{[4,8-bis(azocan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.490nM ΔG°:  -52.6kJ/mole IC50: 8.67nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23633(2-{[4,8-bis(azonan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.770nM ΔG°:  -51.5kJ/mole IC50: 13.6nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457379(CHEMBL4211925)
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23629(2-{[4,8-bis(azepan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.860nM ΔG°:  -51.2kJ/mole IC50: 15.2nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50411998(CHEMBL265689)
Affinity DataIC50: 15.8nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457390(CHEMBL4208680)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50017691(CHEMBL126075 | dilazep)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036308(CHEMBL3353071)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457381(CHEMBL4211194)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50222744(2-amino-6-(4-nitrobenzylthio)-9-beta-D-ribofuranos...)
Affinity DataIC50: 21.4nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50411987(CHEMBL260055)
Affinity DataIC50: 21.9nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457387(CHEMBL4215413)
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457386(CHEMBL4212967)
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409053(6-(5-Fluoro-6-methylpyridin-3-yl)-3,3-dimethyl-1-(...)
Affinity DataIC50: 27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409054(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457385(CHEMBL4207561)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50411986(CHEMBL260166)
Affinity DataIC50: 27.5nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50608216(CHEMBL5277962)
Affinity DataIC50: 30nMAssay Description:Inhibition of ENT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036310(CHEMBL3353073)
Affinity DataIC50: 31nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457378(CHEMBL4203736)
Affinity DataIC50: 31nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412000(CHEMBL410278)
Affinity DataIC50: 31.6nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409033(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 32.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412042(CHEMBL260882)
Affinity DataIC50: 33.1nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409050(1-(6-Cyclopropyl-5-(methylsulfonyl)pyridin-3-yl)-3...)
Affinity DataIC50: 38.5nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457384(CHEMBL4210157)
Affinity DataIC50: 39nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409044(1-(5-(Cyclopropylsulfonyl)pyridin-3-yl)-3,3-dimeth...)
Affinity DataIC50: 40nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409034(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(6-(meth...)
Affinity DataIC50: 40.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409037(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 44.9nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457376(CHEMBL4213616)
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457377(CHEMBL4205790)
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse ENT1 expressed in mammalian cells assessed as reduction in [2,8-H]adenosine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50036306(CHEMBL3353070)
Affinity DataIC50: 66nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412004(CHEMBL260645)
Affinity DataIC50: 69.2nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409049(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 71.7nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM23697(2-({6-[(2-hydroxyethyl)[2-(propan-2-yloxy)ethyl]am...)
Affinity DataKi:  4.30nM IC50: 76nMAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412017(CHEMBL409320)
Affinity DataIC50: 77.6nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Mouse)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM409048(5-(3,3-dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 79.3nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50412007(CHEMBL408710)
Affinity DataIC50: 81.3nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50411995(CHEMBL258627)
Affinity DataIC50: 87.1nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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