Compile Data Set for Download or QSAR
Report error Found 769 of ic50 data for polymerid = 696,50001145
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585537(CHEMBL5084938)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480924(US10906888, Example 138)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480916(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrazin-2-yl)...)
Affinity DataIC50: 0.0410nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480924(US10906888, Example 138)
Affinity DataIC50: 0.0430nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480965(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480965(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 0.0620nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480929(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrimidin-5-y...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480929(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrimidin-5-y...)
Affinity DataIC50: 0.0820nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480917(7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 0.0940nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM408834(US10364255, Ex. 25)
Affinity DataIC50: 0.100nMAssay Description:Method 1:Vanin-1 Enzymatic Assay:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475856(US10864201, Ex. 4.1)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475858(US10864201, Ex. 4.3)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475859(US10864201, Ex. 4.4)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475861(US10864201, Ex. 5.2)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475862(US10864201, Ex. 5.3)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475869(US10864201, Ex. 7.1)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475870(US10864201, Ex. 7.2)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475872(US10864201, Ex. 7.4)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475874(US10864201, Ex. 8.2)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475875(US10864201, Ex. 8.3)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475883(US10864201, Ex. 9.1)
Affinity DataIC50: 0.100nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM668454(US20240124479, Compound 38)
Affinity DataIC50: 0.100nMAssay Description:A certain mass of the compound was weighed precisely, and prepared with DMSO and reaction buffer (50 mM Tris base, 50 mM KCl, 1.6 mM cysteamine, 0.00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480917(7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480956(US10906888, Example 173)
Affinity DataIC50: 0.116nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480956(US10906888, Example 173)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480963(US10906888, Example 180)
Affinity DataIC50: 0.196nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM408835(US10364255, Ex. 26)
Affinity DataIC50: 0.200nMAssay Description:Method 1:Vanin-1 Enzymatic Assay:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM408845(US10364255, Ex. 37)
Affinity DataIC50: 0.200nMAssay Description:Method 1:Vanin-1 Enzymatic Assay:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475866(US10864201, Ex. 5.5)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475868(N-[(3S)-1-[(2R)-2-(4-Fluorophenyl)-2-methyl-1H,2H,...)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475873(US10864201, Ex. 8.1)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475885(US10864201, Ex. 9.3)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475887(N-[(3S)-1-[(2R)-2-(4-Cyanophenyl)-2-methyl-1H,2H,3...)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475890(US10864201, Ex. 11.3)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475907(US10864201, Ex. 13.1)
Affinity DataIC50: 0.200nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM668456(US20240124479, Compound 41)
Affinity DataIC50: 0.200nMAssay Description:A certain mass of the compound was weighed precisely, and prepared with DMSO and reaction buffer (50 mM Tris base, 50 mM KCl, 1.6 mM cysteamine, 0.00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480958(US10906888, Example 175)
Affinity DataIC50: 0.240nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480931(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480931(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-...)
Affinity DataIC50: 0.242nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480971(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrimidin-5-y...)
Affinity DataIC50: 0.277nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480971(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrimidin-5-y...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480837(US10906888, Example 54)
Affinity DataIC50: 0.283nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480926(US10906888, Example 140)
Affinity DataIC50: 0.283nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480957(US10906888, Example 174)
Affinity DataIC50: 0.293nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475889(US10864201, Ex. 11.2)
Affinity DataIC50: 0.300nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475901(US10864201, Ex. 12.2)
Affinity DataIC50: 0.300nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM475909(US10864201, Ex. 13.3)
Affinity DataIC50: 0.300nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 0.300nMAssay Description:A certain mass of the compound was weighed precisely, and prepared with DMSO and reaction buffer (50 mM Tris base, 50 mM KCl, 1.6 mM cysteamine, 0.00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480918(US10906888, Example 132)
Affinity DataIC50: 0.349nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPantetheinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480918(US10906888, Example 132)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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