Compile Data Set for Download or QSAR
Report error Found 19 of ic50 data for polymerid = 6799,10839
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337263(3-(2-chlorobenzyloxy)-2-(2-fluorophenyl)-2H-pyrazo...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50608946(CHEMBL2008708)
Affinity DataIC50: 12nMAssay Description:Inhibition of GABAA alpha2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 22nMAssay Description:Inhibitory effect was measured for [3H]GABA-uptake from rat synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50608947(CHEMBL5281056)
Affinity DataIC50: 24nMAssay Description:Inhibition of GABAA alpha2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337271(2-(4-chlorophenyl)-3-(4-fluorobenzyloxy)-6,7,8,9-t...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337270(2-(4-chlorophenyl)-3-(2-fluorobenzyloxy)-6,7,8,9-t...)
Affinity DataIC50: 154nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337264(2-(benzo[d][1,3]dioxol-5-yl)-3-(2-chlorobenzyloxy)...)
Affinity DataIC50: 155nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337269(3-(4-chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-t...)
Affinity DataIC50: 177nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337275(2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-6,7,8,9-...)
Affinity DataIC50: 185nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337268(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-8,8-dimet...)
Affinity DataIC50: 213nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337274(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2H-pyrazo...)
Affinity DataIC50: 265nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337265(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-t...)
Affinity DataIC50: 271nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337267(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2,6,7,9-t...)
Affinity DataIC50: 461nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337272(2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-2H-pyraz...)
Affinity DataIC50: 472nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337266(3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2,6,7,8,9...)
Affinity DataIC50: 605nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50329649(1-phenylethyl 9H-pyrido[3,4-b]indole-3-carboxylate...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant GABAA alpha2 receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337277(2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-8-(1H-im...)
Affinity DataIC50: 2.11E+3nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337276(3-(2-chlorophenoxy)-2-(4-chlorophenyl)-6,7,8,9-tet...)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed