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TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 0.800nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679658(US20240182487, Compound 1)
Affinity DataIC50: 2.10nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679664(US20240182487, Compound 63)
Affinity DataIC50: 2.80nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 3.60nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679663(US20240182487, Compound 62)
Affinity DataIC50: 4.10nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679660(US20240182487, Compound 3)
Affinity DataIC50: 13.2nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679659(US20240182487, Compound 2)
Affinity DataIC50: 22.9nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679666(US20240182487, Compound 65)
Affinity DataIC50: 35.9nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679661(US20240182487, Compound 16)
Affinity DataIC50: 38.4nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM679698(US20240182487, Compound 99)
Affinity DataIC50: 8.53E+3nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent