Compile Data Set for Download or QSAR
Report error Found 46 of ic50 data for polymerid = 6500,49000434,50002104
TargetCorticotropin-releasing factor receptor 2(Human)
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WIPO
LigandPNGBDBM581978(WO2023285347, Compound 1 | DNPSLSIDLTFHLLRTLLELART...)
Affinity DataIC50: 0.120nMAssay Description:Receptor SPA binding assays were performed in white 96-well plates in a total volume of 200 mI per well. Freeze dried analogues were dissolved in 80%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2023285347

TargetCorticotropin-releasing factor receptor 2(Human)
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WIPO
LigandPNGBDBM50026978(CHEMBL2368116)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026954(CHEMBL2370929)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119602(D L S D-phe His L L R K Nleu I E I E K Q E K E K G...)
Affinity DataIC50: 0.570nMAssay Description:Compound was evaluated for affinity towards Corticotropin releasing factor receptor 2 expressing tissues such as Choroid plexus, blood vesselsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
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WIPO
LigandPNGBDBM50026959(CHEMBL2370916)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
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WIPO
LigandPNGBDBM581979(WO2023285347, Compound 2 | IVLSLDVPIGLLQILLEQARARA...)
Affinity DataIC50: 0.580nMAssay Description:Receptor SPA binding assays were performed in white 96-well plates in a total volume of 200 mI per well. Freeze dried analogues were dissolved in 80%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2023285347

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026983(CHEMBL2370926)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026976(CHEMBL2370933)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50370170(CHEMBL1794009)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026956(CHEMBL2370938)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026982(CHEMBL2370927)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026961(CHEMBL2370915)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026981(CHEMBL2370939)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026946(CHEMBL2370917)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026980(CHEMBL2370940)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50158983(CHEMBL439883 | E G P P I S I D L S L E L L R K M I...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026965(CHEMBL2370914)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 2.10nMAssay Description:Compound was evaluated for affinity towards Corticotropin releasing factor receptor 2 expressing tissues such as Choroid plexus, blood vesselsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026984(CHEMBL2369694)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026950(CHEMBL2369741)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026977(CHEMBL2370931)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026949(CHEMBL2370930)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50370167(CHEMBL1794010)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026988(CHEMBL2370920)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50370166(CHEMBL1794007)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026985(CHEMBL2369693)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50370163(CHEMBL1794006)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026986(CHEMBL2370924)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026987(CHEMBL2370921)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026979(CHEMBL2370941)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50026955(CHEMBL2369740)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131860(US8835444, 1.8)
Affinity DataIC50: 727nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131882(US8835444, 5.27)
Affinity DataIC50: 2.03E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131869(US8835444, 3.6)
Affinity DataIC50: 3.74E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131868(US8835444, 3.3)
Affinity DataIC50: 4.63E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131880(US8835444, 5.21)
Affinity DataIC50: 4.85E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131858(US8835444, 1.1)
Affinity DataIC50: 4.88E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM131863(US8835444, 2.4)
Affinity DataIC50: 4.94E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50152049(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50152038(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50135329({5-[(Cyclopropylmethyl-propyl-amino)-methyl]-4-tri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Effective concentration against Corticotropin releasing factor receptor 2 in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor assessed as inhibition of CRF-induced intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50460168(CHEMBL4225709)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2beta receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50460168(CHEMBL4225709)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2alpha receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Novo Nordisk

WIPO
LigandPNGBDBM50318666(NITD609 | (1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to human recombinant CRF2alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed