Compile Data Set for Download or QSAR
Report error Found 832 of ic50 data for polymerid = 6461,7890,49000438,49000447,49000450,50002965
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [3H]-SCH 23390 from human recombinant dopamine D1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 0.300nMAssay Description:In vivo binding affinity against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM86180(NSC_5018 | CAS_87075-17-0 | SCH 23390 | SCH23390 |...)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [3H]SCH23390 from human recombinant Dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM86180(NSC_5018 | CAS_87075-17-0 | SCH 23390 | SCH23390 |...)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [3H]SCH 23390 from human recombinant dopamine D1 receptor expressed in CHO cells measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029385((4R,5R)-8-Chloro-3,4,5-trimethyl-5-phenyl-2,3,4,5-...)
Affinity DataIC50: 0.370nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 0.370nMAssay Description:Antagonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as inhibition of dopamine-induced cAMP production incubated for 1...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 0.570nMAssay Description:Binding affinity against Dopamine receptor D1 by using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 0.660nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029378(4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...)
Affinity DataIC50: 0.680nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029370(4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...)
Affinity DataIC50: 0.710nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029370(4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...)
Affinity DataIC50: 0.710nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029387(4-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-1,2,2-trim...)
Affinity DataIC50: 0.760nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029375(4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isop...)
Affinity DataIC50: 0.820nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029375(4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isop...)
Affinity DataIC50: 0.820nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029377(1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimeth...)
Affinity DataIC50: 0.840nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029382(9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6-meth...)
Affinity DataIC50: 0.850nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029395(8-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-5-meth...)
Affinity DataIC50: 0.890nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029383(2-{9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6,9...)
Affinity DataIC50: 1nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029384(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2...)
Affinity DataIC50: 1nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]- #NAME from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 1.01nMAssay Description:Tested for its affinity towards Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029400(3-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50007567(CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...)
Affinity DataIC50: 1.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50012961(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo...)
Affinity DataIC50: 1.20nMAssay Description:In vivo binding affinity against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50007567(CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...)
Affinity DataIC50: 1.20nMAssay Description:Ability to displace [3H]-SCH- 23390 (0.2 nM) from corpus striatum of rat Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 1.30nMAssay Description:In vitro binding affinity towards rat Dopamine receptor D1 by [3H]SCH-23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029378(4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029377(1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimeth...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029408(4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human dopamine D1 receptor expressed in CHO-K1 cells by cAMP Hunter assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029369(4-(6-Chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-p...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human recombinant at D1 receptor assessed as inhibition of dopamine-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029390(4-[6-Bromo-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-t...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029394(2-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-octahy...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029393(4-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-1,2,2-...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029371(1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-3,3-di...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50287046(8-Chloro-5-(3-isothiocyanato-phenyl)-3-methyl-2,3,...)
Affinity DataIC50: 2.10nMAssay Description:Compound was tested for binding affinity against Dopamine receptor D1 using 1 nM [3H]SCH-23390 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article

TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 2.15nMAssay Description:Binding affinity against Dopamine receptor D1 by using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50007568(CHEMBL303313 | 1-(8-Chloro-10,11-dihydro-dibenzo[b...)
Affinity DataIC50: 2.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM22872(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Affinity DataIC50: 2.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50007568(CHEMBL303313 | 1-(8-Chloro-10,11-dihydro-dibenzo[b...)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity towards dopamine receptor D1 by displacement of [3H]-SCH- radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50007568(CHEMBL303313 | 1-(8-Chloro-10,11-dihydro-dibenzo[b...)
Affinity DataIC50: 2.20nMAssay Description:Ability to displace [3H]-SCH- 23390 (0.2 nM) from corpus striatum of rat Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029392(4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2-di...)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 2.52nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM86180(NSC_5018 | CAS_87075-17-0 | SCH 23390 | SCH23390 |...)
Affinity DataKi:  1.24nM ΔG°:  -51.7kJ/mole IC50: 2.52nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029389(1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50029374(4-[3-(4-Fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl...)
Affinity DataIC50: 3nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50202337(3-Iodoboldine | (S)-3-iodo-1,10-dimethoxy-6-methyl...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of SKF38393-induced cAMP accumulation measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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