Compile Data Set for Download or QSAR
Report error Found 122 of ic50 data for polymerid = 619
TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403299(US10329307, Example 46)
Affinity DataIC50: 240nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403270(US10329307, Example 17)
Affinity DataIC50: 290nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370580(US10238638, Example 9)
Affinity DataIC50: 330nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403298(US10329307, Example 45)
Affinity DataIC50: 370nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403263(US10329307, Example 10)
Affinity DataIC50: 390nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403254(US10329307, Example 1)
Affinity DataIC50: 420nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403265(US10329307, Example 12)
Affinity DataIC50: 420nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403275(US10329307, Example 22)
Affinity DataIC50: 440nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403286(US10329307, Example 33)
Affinity DataIC50: 440nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403272(US10329307, Example 19)
Affinity DataIC50: 460nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403271(US10329307, Example 18)
Affinity DataIC50: 470nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403296(US10329307, Example 43)
Affinity DataIC50: 480nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403269(US10329307, Example 16)
Affinity DataIC50: 500nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403292(US10329307, Example 39)
Affinity DataIC50: 510nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403274(US10329307, Example 21)
Affinity DataIC50: 540nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403291(US10329307, Example 38)
Affinity DataIC50: 540nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403266(US10329307, Example 13)
Affinity DataIC50: 550nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403290(US10329307, Example 37)
Affinity DataIC50: 560nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403276(US10329307, Example 23)
Affinity DataIC50: 600nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403287(US10329307, Example 34)
Affinity DataIC50: 700nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403273(US10329307, Example 20)
Affinity DataIC50: 710nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403308(US10329307, Example 55 | US10329307, Example 57 | ...)
Affinity DataIC50: 720nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403264(US10329307, Example 11)
Affinity DataIC50: 740nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403308(US10329307, Example 55 | US10329307, Example 57 | ...)
Affinity DataIC50: 740nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403289(US10329307, Example 36)
Affinity DataIC50: 750nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403297(US10329307, Example 44)
Affinity DataIC50: 750nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370593(US10238638, Example 22)
Affinity DataIC50: 760nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403278(US10329307, Example 25)
Affinity DataIC50: 790nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403316(US10329307, Example 63 | US10329307, Example 65 | ...)
Affinity DataIC50: 820nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403288(US10329307, Example 35)
Affinity DataIC50: 840nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403283(US10329307, Example 30)
Affinity DataIC50: 860nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403316(US10329307, Example 63 | US10329307, Example 65 | ...)
Affinity DataIC50: 860nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403284(US10329307, Example 31)
Affinity DataIC50: 890nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403308(US10329307, Example 55 | US10329307, Example 57 | ...)
Affinity DataIC50: 920nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370592(US10238638, Example 21)
Affinity DataIC50: 920nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370620(US10238638, Example 67)
Affinity DataIC50: 930nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403262(US10329307, Example 9)
Affinity DataIC50: 950nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403277(US10329307, Example 24)
Affinity DataIC50: 950nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403282(US10329307, Example 29)
Affinity DataIC50: 950nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370581(US10238638, Example 10)
Affinity DataIC50: 980nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403300(US10329307, Example 47)
Affinity DataIC50: 1.00E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403316(US10329307, Example 63 | US10329307, Example 65 | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403295(US10329307, Example 42)
Affinity DataIC50: 1.10E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403301(US10329307, Example 48)
Affinity DataIC50: 1.10E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403305(US10329307, Example 52)
Affinity DataIC50: 1.10E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370497(US10238638, Example 5)
Affinity DataIC50: 1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370613(US10238638, Example 42)
Affinity DataIC50: 1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403256(US10329307, Example 3)
Affinity DataIC50: 1.20E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM403312(US10329307, Example 59)
Affinity DataIC50: 1.20E+3nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370591(US10238638, Example 20)
Affinity DataIC50: 1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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